Searchable abstracts of presentations at key conferences in endocrinology

ea0038fut2.1 | Futures 2: Overcoming the consultancy hurdle | SFEBES2015

Kar Partha

Much has been written and discussed about the role of the specialist within the confines of the modern NHS. There is a growing realisation that having a specialist rigidly based in hospital is becoming difficult to sustain; instead, flexibility is now crucial as primary and specialist care look to work together to improve diabetes care.With the challenges of the Five Year Forward View (NHS England, 2014) upon us in England, and similar pressures elsewher...

ea0013p35 | Clinical practice/governance and case reports | SFEBES2007

Pregnancy, hyperaldosteronism and an adrenal mass – were we Conned?

Kar Partha , Cummings Michael

A 30 year old woman presented at 15 weeks gestation with resistant hypertension (that had been diagnosed prior to pregnancy) and hypokalaemia (2.8 mmol/l). Subsequent tests, whilst on Nifedipine, showed a markedly raised aldosterone/renin ratio of 267 (n<25) [Aldosterone 720 ng/L;Renin 3 mu/L] (Aldosterone reference range: Supine:20–190 ng/L, Ambulant 30–340 ng/L; Renin reference range: Supine 2–30 mu/L, Ambulant 3–40 mu/L).<p class="a...

ea0012p64 | Endocrine tumours and neoplasia | SFE2006

A probable PTH- secreting metastatic breast carcinoma

Kar P , Meeking D

A 50-year-old woman was admitted to hospital feeling unwell.Biochemistry: Calcium 3.46 (2.15–2.6),PO4 0.42 (0.8–1.5), AlkalinePhosphatase 259 (30–95). She had been diagnosed 3 years ago with Carcinoma breast and had undergone surgery,chemotherapy and radiotherapy. Regular follow-up had not shown any recurrence.No breast lump or bony tenderness was recorded.Further biochemistry: PTH 30 (0–6...

ea0025p199 | Endocrine tumours and neoplasia | SFEBES2011

A case of phaeochromocytoma of the urinary bladder

Bujanova Jana , Mongolu Shiva , Kar Partha

Introduction: Phaeochromocytoma of the urinary bladder is a rare neoplasm and accounts for <1% of all phaeochromocytomas. It is more common in females and the majority of patients present in second and fourth decade. Its common presentation is painless haematuria, headache, palpitation, hypertension and syncope during or immediately after urination.Case history: We present a case of 48-year-old man who presented to Endocrinology with a few months his...

ea0021p331 | Steroids | SFEBES2009

Group education improves patient confidence in managing steroid sick day rules

Munday Linda Jean , Chong Lina , Kar Partha

Background: Group education for patients with diabetes is a well validated method of enhancing self-management skills. More recently some departments have used group education to teach endocrine patients how to administer IM hydrocortisone.Innovation: Patients on steroid replacement, identified by the endocrine nurse and GPs, were invited to attend a group session. The aim was to ensure every relevant patient in the locality had the opportunity to be edu...

ea0019p165 | Endocrine tumours and neoplasia | SFEBES2009

Adrenal insufficiency in post chemotherapy patients: an often missed diagnosis.

Kalathil S , Simon G , Kar P

A 75-year-old gentleman was admitted with symptoms of lethargy, abdominal pain, severe nausea and vomiting in January 2008. He had solid transitional cell carcinoma of the bladder, diagnosed in May 2005, when he initially presented with microscopic haematuria. He had further undergone radical cystoprostatectomy and an ileal conduit. The histology showed aggressive tumour (G3pT3a) with vascular invasion but no metastasis. Follow-up CT scans done 9 months later showed a 3.5 cm l...

ea0019p231 | Pituitary | SFEBES2009

Acromegaly: the contribution of prolactin in the management

Lambert KD , Munday LJ , Kar PS

History: A 62-year-old female presented with a 15-year history of tiredness and headaches. Clinically she had signs of acromegaly. This was confirmed with IGF1 688 ug/l and with a 2 h value (post GTT)of growth hormone 13.9 miu/l. MRI scan revealed a 3.5×3.5×2.5 cm mass in the pituitary fossa extending laterally to involve the left cavernous sinus and suprasellar extension causing moderate splaying of the optic chiasm. The left trigeminal nerve and internal carotid ar...

ea0019p362 | Thyroid | SFEBES2009

A case of papillary carcinoma associated with Cowdens syndrome

Lambert KD , Gorman B , Kar PS

History and examination: A 46-year-old gentleman presented with right sided goitre which had increased in size over one month. He previously had a left thyroidectomy for non-toxic goitre.As a child he had several lipomas removed. On examination he has mucosal neuromas, an AV malformation on his left wrist, white papules on his hands and trichilemmonas on his legs. He has macroencephalopathy, 64.4 cm round. The right lobe of the thyroid was enlarged and h...

ea0065p333 | Neuroendocrinology | SFEBES2019

A rare case of metastatic insulinoma

Millar Kate , Sim Sing Yang , Haider Najaf , Kar Partha

A 24 year old gentleman presented following an episode where he became ‘sleepy’ and disorientated whilst driving and had to pull over. He was confused and lethargic and paramedics found blood glucose of 2 mmol/l. He gave a 3-week history of extreme lethargy, nausea, epigastric discomfort, blurring of vision and constant hunger. He denied recent weight changes and had no significant past medical/family history. Biochemical evaluation was as follows; Laboratory glucose...

ea0065p384 | Reproductive Endocrinology and Biology | SFEBES2019

Its not just the baby that grows in pregnancy

Haider Najaf , Butt Nouman , Millar Kate , Kar Partha

Pituitary apoplexy is a rare but life threatening condition if not diagnosed and treated promptly. Common causes include hypertension, head trauma, major surgery, dynamic pituitary tests, anticoagulant use and pregnancy. In pregnancy, hyperplasia and hypertrophy of the lactotroph cells increase pituitary volume by 45% returning to original size at 6 months post-partum. Pituitary apoplexy is uncommon in pregnancy and an underlying adenoma is usually the cause. Very few...