Searchable abstracts of presentations at key conferences in endocrinology

ea0031p383 | Thyroid | SFEBES2013

Case report: when measured free T4 and free T3 may be misleading. Interference with free thyroid hormones measurements on Roche and Siemens platforms

Lewandowski Krzysztof , Dabrowska Katarzyna , Lewinski Andrzej

A 59-year-old female presented with apathy and 6 kg weight gain. Investigations revealed primary hypothyroidism (TSH >100 μIU/ml). Thyroxine (L-T4) was started and titrated up to 75 μg, o.d., with clinical improvement. Other investigations revealed high titres of anti-thyroid peroxidase and anti-thyroglobulin antibodies. After three months, there was a fall in TSH to 12.74 μIU/ml, however, with unexpectedly high free T4 (...

ea0077p249 | Thyroid | SFEBES2021

Pulse methylprednisolone as preparation for thyroidectomy for drug-resistant amiodarone-induced thyrotoxicosis

Lewandowski Krzysztof , Dabrowska Katarzyna , Gluchowska Monika , Lewinski Andrzej

Background: Amiodarone-induced thyrotoxicosis is sometimes extremely difficult to treat necessitating emergency thyroidectomy with perioperative risks including possible thyroid storm. We obtained near normalization of free T3 (FT3) by pulse Methylprednisolone prior to thyroidectomy for drug-resistant Amiodarone-induced thyrotoxicosis.Case Description: A 56 year old man (BMI 29.7 kg/m2), with history atrial flutter/fibrillation, episodes of fa...

ea0034p54 | Clinical practice/governance and case reports | SFEBES2014

Thyrotoxicosis after severe hypothyroidism in a patient with a history of Hodgkin's lymphoma and neck irradiation

Lewandowski Krzysztof , Dabrowska Katarzyna , Makarewicz Jacek , Lewinski Andrzej

Background: Neck irradiadion is associated with several complications including both hypo- and hyperthyroidism. We present a case of severe hypothyroidism, followed 5 years later by thyrotoxicosis.Case description: A 27-year-old female presented with clinical and biochemical thyrotoxicosis (TSH 0.01 μIU/ml (ref. range: 0.27–4.2 μIU/ml); FreeT4 1.58 ng/dl (ref. 0.98–1.63 ng/dl); FreeT3 4.56 pg/ml (ref. 2.6–4....

ea0014p7 | (1) | ECE2007

Effects of melatonin on glutathione peroxidase activity after adriamycin in normal and pinealectomized rats

Dabrowska Katarzyna , Stuss Michal , Gromadzinska Jolanta , Wasowicz Wojciech , Sewerynek Ewa

Adriamycin (ADR) is a potent chemotherapeutic agent, effective in treatment of leukemias, lymphomas and of many solid tumours. However, its clinical usage is often limited by cardiotoxicity, induced by oxygen radical damage of membrane lipids.Melatonin (MEL), is a well-known antioxidant. It has been shown that melatonin can scavenge free radicals, both directly or indirectly, stimulating the activity of antioxidative enzyme, e.g., glutathione peroxidase ...