Searchable abstracts of presentations at key conferences in endocrinology

ea0034p21 | Bone | SFEBES2014

Predictors of postoperative hypocalcaemia in parathyroidectomy patients: local audit

Katreddy Venkata , Blundell David , Buch Harit

Introduction: Parathyroidectomy is the treatment of choice for patients with primary hyperparathyroidism who have significant hypercalcemia and/or end-organ damage. The incidence of postoperative hypocalcaemia is 25–90% in patients with evidence of radiological evidence of parathyroid disease, 0–6% without. In most patients it is mild, but in some, it can cause significant morbidity. It has been attributed as ‘hungry-bone syndrome’ and attempts have been ma...

ea0028p97 | Clinical practice/governance and case reports | SFEBES2012

Unusual presentation, multi speciality effort and excellent outcome – A case of ovarian carcinoid

Mathew Anna , Katreddy Venkata , Buch Harit

Carcinoid tumours are the commonest neuroendocrine tumours (50%), with a prevalence of 3–5/100,000. 10% present with carcinoid syndrome due to release of kinins and serotonin, released directly from the tumour in to the blood or due to liver metastases. Carcinoid heart disease due to ovarian carcinoid is extremely rare. Here we present such a case. A 69 year old female presented to surgeons with increased bowel frequency and weight loss. Blood tests, colonoscopy and biops...

ea0025p33 | Clinical biochemistry | SFEBES2011

Cross reactivity of Spironolactone with androstenedione immunoassay

Katreddy Venkata , Bdiri Ashraf , Ashawesh Khaled

Introduction: Hirsutism, the presence of terminal (coarse) hairs that appear in a male-like pattern, affects 5–10% of women and may cause concern for an underlying endocrine disorder or malignancy. Spironolactone compete for the androgen receptor in the hair follicle, therefore, it is frequently used in treatment of hirsutism. We report a case, in which treatment of hirsutism with Spironolactone interfered with androstenedione immunoassay and raised unnecessary concern ab...

ea0025p303 | Steroids | SFEBES2011

Accidental long-term ingestion of androgenic steroid in a young female: a case report

Katreddy Venkata , Dale Jane , Siddique Haroon

Aim: We present an unusual case of long-term accidental ingestion of androgenic steroid in a young female.Case: A 28-year-old lady presented with male pattern of hair growth, weight gain of three stones, change in voice, and secondary amenorrhea. On direct questioning she admitted she was taking ‘fat bursting pills’ for nearly 6 months, obtained from a gym, to lose weight. Examination revealed a blood pressure of 150/77 mmHg, increased muscle b...

ea0034p411 | Thyroid | SFEBES2014

A rare case of papillary thyroid cancer arising from the ovary

Katreddy Venkata , Buch Harit , Pettit Laura , Oguntolu Victor

Background: Struma ovarii, defined as containing 50% or more thyroid tissue is rare and accounts for 1% of ovarian tumours. Presentation is non-specific, relating to mass effect. Although the tumour predominantly consists of thyroidal tissue, features of hyperthyroidism occur in <5% of cases. Majority are benign, histological features of thyroid cancer are found in about 5–10%. Seventy per cent of these are papillary thyroid cancer (PTC). We present a case of struma o...

ea0025p329 | Thyroid | SFEBES2011

Hypothyroidism and adrenaleukodystrophy, a rare association

Katreddy Venkata , Bdiri Ashraf , Al-Akbar Azizul Aziz , Ashawesh Khaled

Introduction: Adrenaleukodystrophy is an X linked disorder associated with functional defect of very long fatty acid (VLFCA) oxidation leading to accumulation of VLFCA in the white matter of brain and adrenal cortex. It usually presents with adrenal insufficiency and neurological problems and has association with other autoimmune conditions reported so far including vitiligo, ulcerative colitis. We report a case of adrenaleukodystrophy, vitiligo and hypothyroidism.<p class...

ea0034p189 | Neoplasia, cancer and late effects | SFEBES2014

Multiple endocrine neoplasia type 2A in a large family with a C620G mutation of the RET proto-oncogene: diagnostic, treatment, and ethical challenges

Raghavan Rajeev , Katreddy Venkata , Leiw L , Garnham A , Gama R , Strouhal P , Buch H , Viswanath A , Singh BM

Introduction: Multiple endocrine neoplasia type 2 (MEN2) is an autosomal dominant multi-glandular tumour syndrome, caused by RET germline mutations.We present a family with three affected generations identified by predictive testing.Index case and cohort details: A 40-year-old lady referred to ENT clinic with a swelling in the neck. Ultrasound confirmed multinodular goitre with FNAC-THY3. Diagnostic hemithyroidectomy was followed by total thyroidectomy f...

ea0025p20 | Bone | SFEBES2011

Localisation studies in primary hyperparathyroidism: our experience

Katreddy Venkata , Al-akbar A N B Abduk Aziz , Bdiri Ashraf , Ball Andrew , Ashawesh Khaled

Introduction: Primary hyperparathyroidism is not an uncommon disease with incidence of ~25–30 cases per 100 000 people, whether caused by adenoma or hyperplasia, can be cured surgically with a high rate of success. Over past decade minimally invasive surgery has become mainstay of treatment compared to traditional bilateral exploration approach. Accurate preoperative localisation of parathyroid disease is absolutely imperative for effective minimally invasive surgery....

ea0022p450 | Endocrine tumours &amp; neoplasia (<emphasis role="italic">Generously supported by Novartis</emphasis>) | ECE2010

Unusual cause of hyercalcemia in pheochromocytoma

Katreddy Venkata M R , Ashawesh Khalid , Saraf Sanjay , Fiad Tarek M

Introduction: Hypercalcemia with pheochromocytoma usually occurs as part of MEN syndrome associated with parathyroid adenomas or hyperplasia. Here, we present a case of malignant pheochromocytoma with hypercalcemia caused by the secretion of PTHrP secretion tumour itself. Hypercalcemia was corrected on by the removal of the malignant pheochromocytoma.Case: A 75-year-old gentleman with PMHx of hypertension presented with a history of fall and head injury ...