Endocrine Abstracts

Introduction: HIV infection has been associated with bone loss and increased frequency of bone fractures. The main pathogenetic mechanisms involve the direct effect of the virus and the HIV-induced inflammatory cytokines on bone metabolism, the effect of antiretroviral therapy (cART) per se and the frequently coexisting nutritional disorders and hypogonadism, further accelerating bone loss. Bisphosphonates remain the first-line treatment for these patients. Limited da...

IntroductionGlucagon-like peptide 1 receptor agonists (GLP-1RA) and sodium-glucose cotransporter-2 inhibitors (SGLT2i) are the two novel classes of anti-diabetic agents with compelling efficacy, in terms of glucose-lowering and cardio-renal protection. Euglycemic diabetic ketoacidosis (EDKA) is a serious rare adverse effect of SLT2i while the use of GLP-1RA has been scarcely linked with acute pancreatitis in humans.Case presentatio...