Searchable abstracts of presentations at key conferences in endocrinology

ea0077p101 | Neuroendocrinology and Pituitary | SFEBES2021

Worst headache of my life

Kejem Helmine , Mahmud Ahmad , Yusuf Mohamoud

Introduction: Pituitary apoplexy is a rare clinical syndrome secondary to abrupt haemorrhage or infarction of the pituitary gland. It complicates 2-12% of pituitary tumour, most commonly in the setting of non-functioning adenomas 1. We are reporting a case on the evolving apoplexy. A 28-year-old male with sudden onset stabbing type frontal headache at night. He described this as the worst headache in his life. CT scan of head at presentation showed a 1.9 m lesion in the pituit...

ea0086p224 | Metabolism, Obesity and Diabetes | SFEBES2022

The importance of identifying severe hyponatraemia early in hospitalised patients and early referral to endocrinology. Our experience in a large secondary care teaching hospital

Williams Scott , Kejem Helmine , Sun Leong King

Background: Hyponatraemia is known to be associated with significantly increased mortality in hospitalised patients. We identified the number of cases of hyponatraemia referred for an endocrine opinion in our hospital, examined the causes present, and assessed how the speed of referral to endocrinology could affect the management. Methods: Inpatient referrals were audited over a 6-month period from 1st October 2021 to 30th April 2022. Data regarding the ...

ea0074ncc66 | Highlighted Cases | SFENCC2021

Diagnostic dilemma of cushing disease

Kejem Helmine , Chattington Paula , Mahmud Ahmad

57 year old female physiotherapist, diagnosed with osteoporosis following a fibula fracture from a low impact stretch and a wedge vertebral fracture at age 51 with a metatarsal fracture age 54. With associated history of easy bruising, increase abdominal girth although her weight remained stable at 48.5 kg with BMI 19.9 and proximal myopathy. Blood pressure was constantly normal. Investigations: Early morning random Cortisol 564 and ACTH 6.6 (2–11), cort...

ea0081p243 | Thyroid | ECE2022

Resistant Graves’ thyrotoxicosis with adverse cardiovascular effects

Williams Scott , Kejem Helmine , Nizza Jael , Srinivas Shankar Upendram

A 61-year-old lady presented to her general practitioner in July 2018 with weight loss, loose stools, hair loss, increased anxiety and dry eyes over several weeks. Blood tests revealed Graves’ thyrotoxicosis (TSH< 0.10 mU/l, (RR) 0.30-5.50 mU/l; Free T4 (fT4) 26.1 pmol/l, RR 11.5−22.7 pmol/l; Free T3 (fT3) 11.8 pmol/l, RR 0.0-7.0 pmol/l, thyroid receptor antibodies >40.0U/l, RR 0.0-1.8 U/l; thyroid peroxidase antibodies 173.0 iu/ml, RR 0.0-33.9 iu/ml). There...

ea0081ep938 | Reproductive and Developmental Endocrinology | ECE2022

Importance of karyotyping in the evaluation of male hypogonadism

Thuzar Aung Ei , Srinivas Sanjana , Kejem Helmine , Srinivas-Shankar Upendram

We present the case history of a 48-year-old man with anxiety and depression, who was referred for evaluation of absent libido, long standing erectile dysfunction and reduced body hair. There was no history of orchitis, pituitary problems or low impact fractures. He was always single and did not father children. Clinical examination revealed obesity (BMI 31 kg/m2), absent facial hair, reduced body, axillary and pubic hair. There was bilateral gynaecomastia. The phallus was nor...

ea0090ep5 | Adrenal and Cardiovascular Endocrinology | ECE2023

A case of Conn syndrome presenting as persistent post-partum hypertension

Aung Ei Thuzar , Kejem Helmine , Khan Muhammad Ilyas , Thondam Sravan

Introduction: Conn’s syndrome is a well-known cause of secondary hypertension; however, its association with pregnancy is rare. We discuss an interesting case of Conn syndrome presented with severe hypertension 8 weeks post-partum.Case report: A 34-years-old lady, previously fit and well, presented with severe hypertension (blood pressure–189/115 mmHg) and hypokalaemia (K-2.5 mmol/l) at 8 weeks post-partum. Antenatal records indicated she was n...

ea0091p13 | Poster Presentations | SFEEU2023

Phaeochromocytoma in pregnancy: not all hypertension is essential

Mankumare Mohitraje , Kejem Helmine , Myers Jenny , Mumby Clare

Case history: We report a case of a 36-year-old female. She was Para 1 and 10 years prior had a vaginal delivery of a normal sized infant after an uncomplicated pregnancy. She was subsequently diagnosed with hypertension managed with Ramipril-10mg. She booked in her second pregnancy at 12 weeks/gestation. Ramipril had been stopped at positive pregnancy test and booking blood pressure was 139/85. Labetalol was commenced and she was seen in the pregnancy hypertension clinic....

ea0081p553 | Calcium and Bone | ECE2022

Case report: an unusual presentation of hypercalcaemia in pregnancy

Williams Scott , Kejem Helmine , Wynne Sian , Nizza Jael , Tildesley Rachel , Shore Susannah , Lim Rebecca

A 26-year-old Caucasian female presented at 14 weeks gestation with a 6-week history of lethargy, nausea and vomiting during her first pregnancy. Her adjusted Calcium was 4.12 mmol/l and parathyroid hormone (PTH) 26 pmol/l, consistent with possible primary hyperparathyroidism. She was previously well apart from occasional migraines. There was no known history of familial hypercalcaemia or MEN. Other biochemistry results revealed hypokalaemia of 3.2 mmol/l, low vitamin D at 16 ...

ea0081ep168 | Calcium and Bone | ECE2022

Hypercalcemia in sarcoidosis unmasked by treatment with Vitamin D

Kejem Helmine , Williams Scott , George Emmanuel , Chiu Yee Ho , Shankar Upendram Srinivas

We present the case history of a 62 year old male, who was recently diagnosed with sarcoidosis which was confirmed on biopsy of a calf nodule. CT scan revealed pulmonary involvement. Our patient had low vitamin D 12 nmol/l (nr 50–100) and initial adjusted calcium was 2.48 mmol/l (2.13–2.63). DEXA bone density scan revealed osteopenia. He was commenced on loading dose of colecalciferol 40,000 units weekly and received 3 doses. He presented 1 month later with polydipsi...