Searchable abstracts of presentations at key conferences in endocrinology

ea0086p337 | Metabolism, Obesity and Diabetes | SFEBES2022

A case of GLP-1 RA-induced hypoglycaemia following RYGB in a patient with Type II Diabetes and autonomic dysfunction

Jones Sophie , Kenkre Julia , Tan Tricia

Background: Increased endogenous post-prandial GLP-1 release is a key mediator of improved glycaemic control following Roux-en-Y gastric bypass (RYGB) surgery. GLP-1 receptor agonists (GLP-1 RA) augment glucose-stimulated-insulin-release and suppress glucagon release, and do not usually cause hypoglycaemia. The use of GLP-1 RA have been shown to be safe for patients requiring additional glycaemic control following RYGB. We present a case of severe recurrent fasting nocturnal h...

ea0021p297 | Pituitary | SFEBES2009

Should we take macroprolactinoma patients off dopamine agonists at 3 or 5 years as they almost invariably recur?

Scott Rebecca , Barber Thomas , Kenkre Julia , Garnet Catherine , Wass John

Objective: Our objective was to examine recurrence of hyperprolactinaemia following discontinuation of dopamine agonist (DA) therapy in patients with macroprolactinoma who have had treatment for 3–15 years.Methods: We identified retrospectively adult patients (n=15) attending OCDEM (Churchill Hospital, Oxford, UK) with a confirmed diagnosis of macroprolactinoma (established during the last 25 years), who had been treated with DA therapy for a...

ea0086p217 | Metabolism, Obesity and Diabetes | SFEBES2022

Ethnic differences in diabetes remission following bariatric surgery

Cardillo Luca , Stephanie Kenkre Julia , Rashid Ahmed Ahmed , Purkayastha Sanjay , Tsironis Christos , Tan Tricia

Background and Aim: Type 2 diabetes mellitus (T2DM) disparately affects ethnic groups. Prevalence is higher in Asian and Black ethnicities, and these patients suffer increased rates of some diabetes-related complications. Bariatric surgery is an effective treatment for T2DM and can lead to complete diabetes remission. The aim of this study was to assess if T2DM remission rates at 1-year following bariatric surgery vary between different ethnicities.Metho...

ea0053cd2.1 | Case Discussions: complex clinical cases 2.0 | OU2018

Eating behaviour and psychological relationship to food following Roux-en-Y Gastric bypass surgery or VLCD intervention: insights into mechanisms of sustained weight loss

Alessimii Haya , Perez-Pevida Belen , Scholtz Samantha , Kenkre Julia , Doyle Chedie , Ahmed Ahmed , Purkayastha Sanjay , Miras Alexander D , Chahal Harvinder , Tan Tricia

Introduction/Aims: Currently, the most successful long term treatment for obesity is bariatric surgery, however the underlying mechanisms are not fully understood. Changes in gastrointestinal and central neuroendocrine signalling have been postulated as mediators of psychological and eating behaviour changes following bariatric surgery. We aimed to investigate changes in eating behaviour and psychological factors pre- and 1 month post-very low calorie diet (VLCD) and 3-month p...