Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep882 | Thyroid cancer | ECE2015

The rare intracellular RET mutation p.S891A in a Turkish family with hereditary medullary thyroid carcinoma

Keskin Caglar , Gullu Sevim

Introduction: Medullary thyroid carcinoma (MTC) could be familial in 30% of cases. Here, we report a family of FMTC with rarely seen RET p.S891A mutation.Case presentation: A 49-year-old man presented with a single nodule in the left lobe of thyroid. Thyroid ultrasonography (US) showed a nodule and pathological cervical lymph nodes. There was no relevant family history. Fine-needle aspiration cytology (FNAC) of the nodule was consistent with a diagnosis ...

ea0049ep988 | Pituitary - Clinical | ECE2017

Is Pegvisomant correct choice for acromegaly patient with dilated cardiyomypathy?

Cinel Murat , Keskin Caglar , Emral Rifat , Corapcioglu Demet

Objectives: Acromegaly may arise with several clinical presentations and cardiac involvement is the most important factor affecting the course of the disease.Case: A 32-years old man admitted to hospital complaining with shortness of breath. After initial evaluation he was diagnosed as ‘cardiac failure’. Cardiac evaluation revealed that he had ‘dilated cardiomyopathy’ with ejection fraction (EF) of 20%, global hypokinesia without valv...

ea0070aep245 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Assessment of arrhythmia risk due to hypoglycemia with continuous glucose monitoring device and 24-hour holter monitoring

Sahin Mustafa , Keskin Caglar , Cinel Murat , Bahceci Begum , Corapcioglu Demet

Previous studies have shown increased hypoglycemia-associated cardiac arrhythmia and mortality in patients with type 2 diabetes and cardiovascular disease.In this study, we aimed to evaluate the response of gastrointestinal hormones and glucoregulatory hormones to the oral glucose tolerance test in patients who were diagnosed with reactive hypoglycemia and to evaluate the risk of arrhythmia with long-holter ECG measurements in patients with a diagnosis o...

ea0049ep1059 | Pituitary - Clinical | ECE2017

What should central diabetes insipidus and panhypopituitarism point out in a patient with lung adenocarcinoma in remission?

Canlar Sule , Keskin Caglar , Canpolat Asena Gokcay , Gullu Sevim , Corapcioglu Demet

Objectives: Pituitary gland is an uncommon site for metastasis of malignant tumors. Breast and lung are the most common cancer sites. Most pituitary metastases are asymptomatic, with only 7% symptomatic and central diabetes insipidus is the most common symptom.Case presentation: A 54 year-old woman presented with nause, emesis and diplopia to emergency department. Her relatives stated that she had poliuria, nocturia, polidipsia for three months. Her hist...

ea0070aep321 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Severe insulin resistance with cirrhosis: A case report

Durmaz Himmet , Evranos Ogmen Berna , Ahmadova Konul , Kucukcongar Yavas Aynur , Keskin Caglar , Dirikoc Ahmet , Cakir Bekir

Background: Alstrom syndrome is a rare autosomal recessive genetic disorder characterised by vision loss, hearing loss, childhood obesity, insulin resistance and hyperinsulinemia, type 2 diabetes, hypertriglyceridemia, cardiomyopathy, and progressive pulmonary, hepatic, and renal dysfunction. Hyperinsulinemia develops early, and pancreatic islets show beta-cell proliferation, thus suggesting that both insulin resistance and increased insulin secretion might contribute to gluco...

ea0081p504 | Late-Breaking | ECE2022

Adrenal incidentaloma, single center clinical experience

Turan Erdogan Beril , Evranos Ogmen Berna , Keskin Caglar , FAKI Sevgul , Aydin Cevdet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Backgorund: Adrenal incidentalomas (AI) are lesions discovered incidentally on imaging without clinical symptoms or examination findings. AI can produce hormones in 5-30% of cases. Autonomic cortisol secretion (ACS) is the most common of these. Although ACS is asymptomatic, it increases the risk of metabolic disorders.Methods: Patients aged<18 years with adrenal adenoma and upper abdominal MRI who presented and were examined in the endocrinology outp...

ea0090p586 | Calcium and Bone | ECE2023

How well are guidelines followed in the follow-up of hypoparathyroid patients?

Turan Erdogan Beril , Keskin Caglar , Burcak Polat Şefika , Nasiroglu Imga Narin , Ozdemir Didem , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

Background: Hypoparathyroidism (HypoPT) is a rare condition that is characterized by hypocalcemia and hyperphosphatemia due to low or inappropriately normal serum levels of parathyroid hormone (PTH) for at least 6 months. The long-term complications of hypoparathyroidism indicate the necessity of screening them. In the follow-up of these patients according to hypoparathyroidism guidelines is recommended; calcium, phosphorus, albumin, magnesium, creatinine, and eGFR levels shou...

ea0073aep795 | Late Breaking | ECE2021

Severe hypercholesterolemia with primary sclerosing cholangitis

Durmaz Himmet , Arifoglu Unzile , Keskin Caglar , Baser Husniye , Akdogan Kayhan Meral , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

IntroductionHypercholesterolemia may develop due to primary and secondary causes. Diabetes mellitus, hypothyroidism, nephrotic syndrome and liver diseases are among the most common causes of secondary hyperlipidemia. Here, we will present a case with severe hyperlipidemia due to primary sclerosing cholangitis(PSC).CaseA 36-year-old male patient was admitted to our outpatient clinic due to severe hypercholeste...

ea0090ep816 | Pituitary and Neuroendocrinology | ECE2023

A Rare Pituitary Pathology: Patient With Crooke Cell Corticotroph Adenoma

Yiğit Koroğlu Ekin , Aydin Cevdet , Keskin Caglar , Faruk Turkoğlu Omer , Gureşci Servet , Topaloglu Oya , Ersoy Reyhan , Cakir Bekir

However ACTH secreting adenomas are one of the most common functional pituitary tumors, subtypes such as Crooke cell corticotroph adenoma(CCCA) are relatively rare. We present here a patient with CCCA who had severe hypercortisolism mimicking ectopic ACTH syndrome. A 69 years old female patient admitted to emergency department after a fall. On cranial MRI,’a 3.5x2.5x3cm mass appearance with a sellar-suprasellar location, which is compressing the optic chiasm, expanding th...

ea0037ep823 | Pituitary: clinical | ECE2015

Clinical features and treatment outcomes of resistant acromegaly patients: a single-centre study

Demir Ozgur , Canpolat Asena Gokcay , Aydogan Berna Imge , Keskin Caglar , Canlar Sule , Sahin Mustafa , Emral Rifat , Gullu Sevim , Gedik Vedia Tonyukuk , Uysal Ali Riza , Corapcioglu Demet

Introduction: Disease control in acromegaly can be achieved by surgery, medical treatment, and radiotherapy either alone or in combination. The acromegaly patients whom tumour shrinkage cannot be provided or growth hormone levels do not decrease under multiple treatment modalities are designated as resistant acromegaly. We aimed in our study to evaluate the clinical features of resistant acromegaly patients and determine their responds to different treatment modalities.<p ...