Endocrine Abstracts

Introduction: Autoimmune thyroiditis (AIT), also called Hashimoto thyroiditis or chronic lymphocytic thyroiditis is characterized by destruction of the thyroid gland involving apoptosis of thyroid epithelial cells. It usually presents as euthyroidism or subclinically hypothyroidism, rarely as overt hypothyroidism. The cause of Hashimoto’s thyroiditis is thought to be a combination of genetic susceptibility and environmental factors. Bisphenol A (BPA), an endocrine-disrupt...

İntroduction: Gitelman syndrome is characterized with hypokalemia, hypomagnesemia, hypocalciuria, metabolic alkalosis and neurological symptoms like muscle weakness. The association of GS and type 1 diabetes is rare, only described in a few case reports. We report a patient with unusual combination of Gitelman syndrome, Type 1 Diabetes Mellitus whose presentation was erytrocytosis.Case: A 26-year old male was diagnosed as Gitelman’s syndrome 5...

IntroductionPituitary gland tumors constitute approximately 10–15% of primary brain tumors, and posterior pituitary tumors are extremely rare. Granular cell tumor (GCT) is a low grade non-neuroendocrine neoplasm. Here, we will present our case who was found to have GCT during follow-up of diabetes insipidus (DI).CaseA 23-year-old male patient applied to our outpatient clinic for routine control. 12 years...

Objectives: The novel coronavirus disease-2019 (COVID-19) is the fastest-spreading disease worldwide, with over 380 million cases and 5 million deaths. The presence of diabetes mellitus (DM) in patients with COVID-19 was associated with mortality, acute respiratory distress syndrome, disease progression. COVID-19 was progressed with some hematological disorders, especially lymphopenia. Studies implicated that neutrophil-to-lymphocyte ratio (NLR) level can be a reliable marker ...

Von Hippel-Lindau (VHL) syndrome is a pathological condition that causes various clinical symptoms and is difficult to diagnose. The most common pathological lesions are hemangioblastomas of the central nervous system, retinal angiomas, renal clear cell carcinomas, and pheochromocytomas. Here we reposrt a case of likely to be VHL due to his family history.Case: A 33-year-old male suffering from hypertension and a history of hemangioblastoma operated in 2...

Aim: In patients with papillary thyroid carcinoma (PTC), the incidence of subacute thyroiditis (SAT) is thought to be more frequent than estimated. The incidence of thyroid cancer is between 2.3% and 21.1% in Graves’ Disease (GD).Case: A 31-year-old female patient applied with complaints of amenorrhea and hair loss in the 10th postpartum month. There was no history of COVID-19 infection, but Biontech vaccine were administered two years ago. Her fami...

Pentraxin 3 (PTX3) is produced from several cell types in case of inflammation. PTX3 has been investigated in several autoimmune diseases. As Hashimoto disease is an autoimmune disease of thyroid, we investigated the role of PTX3 levels in patients with Hashimoto disease.Objective: The aim of this study was to investigate the relationship between PTX3 and autoimmune thyroiditis.Methods: The study subjects were classified as four gr...

Aim: Papillary thyroid cancer (PTC) accounts for 85% of thyroid cancers. Classical PTC has a 10 year survival rate of over 95%. Although the histopathological diagnosis of thyroid tumors, which started in the 1950s, has improved significantly in the last few decades, the effect of aggressive subtypes on survival has not been fully clarified. In our study, we investigated the effect of aggressive cytologic subtypes on behavior and prognosis in patients followed up with a diagno...

Aim: Dry eye syndrome(DES) is a common finding in patients with thyroid orbitopathy. There are few studies on DES in patients with papillary thyroid cancer (PTC). Retinal pathology may develop in case of vitamin E deficiency, which has antioxidant, anti-inflammatory and anti-apoptotic properties.Materials and Methods: In our study, 29 patients who received radioactive iodine (RAI) treatment (Group 1) and 22 patients who did not receive RAI treatment (Gro...