Searchable abstracts of presentations at key conferences in endocrinology

ea0044p77 | Clinical biochemistry | SFEBES2016

Nine year evaluation of a recall database of thyroid function tests in a combined antenatal-endocrine clinic

Khalily Naveed , Hodgett Sheena , Barton David

Thyroid dysfunction is associated with well-recognised maternal and fetal complications. There is an increase in thyroxine requirement during pregnancy by 25–50% hence close monitoring of thyroid function and dose augmentation is vital in attaining euthyroid status. In our combined antenatal-endocrine clinic we aim to test thyroid function tests (TFTs) at booking, in the second and third trimesters. In order to reduce the need for patients to re-attend the clinic purely f...

ea0041ep363 | Clinical case reports - Thyroid/Others | ECE2016

Ovarian Leydig cell hyperplasia – an unusual cause of hyperandrogenism in a post-menopausal woman with a possible familial link

Ahmad Sajjad , Khalily Naveed , Lee Stuart

A 60-year-old lady was referred with male pattern hair loss and facial hirsutism of 5–7 years duration. She was otherwise well and had two children in their 30s. She was not taking any medication and reported a normal menstrual cycle prior to menopause at the age of 50.Her androgen profile showed a high testosterone level of 6.1 nmol/l (range <2.5), androstenedione 3.8 nmol/l (0.7–3.8), DHEAS 5.7 μm/l (0.80–4.9), SHBG 33 nmol/l, F...

ea0038p81 | Clinical practice/governance and case reports | SFEBES2015

Glycogenic hepatopathy: a tale infrequently told in the diabetes world

Khalily Naveed , Butt Nida , Dixon Anthony

We present the case of a 27-year-old man who was first diagnosed with type 1 diabetes mellitus when he presented with diabetic ketoacidosis (DKA) and during later admissions was found to have grossly abnormal liver function tests. Following diagnosis, his diabetic control has been a challenge to manage despite the patient’s claim he had been taking his insulin ‘religiously’. He has had repeated admissions with DKA and has failed to attend clinic follow-ups on se...

ea0041ep83 | Adrenal cortex (to include Cushing's) | ECE2016

Depression and acute kidney injury – unusual presentation of Addison’s disease

Ahmad Sajjad , Khalily Naveed , Vernavos Petros , Bondugulapati Laxmi Narsimharao

Introduction: Addison’s disease is the commonest cause of primary hypoadrenalism in the western world. Here, we discuss a case of Addison’s with unusual presentation.Case report: A 39-year-old woman with no previous mental health problems was admitted with history of worsening depression over the last 15 months following her divorce. She had low mood and anhedonia in spite of sertraline for more than a year. This was associated with 40 kg weigh...

ea0063p7 | Adrenal and Neuroendocrine Tumours 1 | ECE2019

A rare association of Adrenocortical carcinoma with haematological and breast malignancy in a young female

Shafqat Muhammad Murtaza , Khalily Naveed , Deol Herpret , Naeem Aamir , Dar Shujah

A 20-year-old female admitted under haematology team for acute myeloid leukaemia. During her admission, she had a whole body CT scan and was found to have a left breast lesion (proven on biopsy to have invasive ductal carcinoma) and a right adrenal mass measuring 6.5 × 7.5 cm with radiological features suggestive of an adrenocortical cancer. Biochemical workup showed raised adrenal androgens: DHA Sulphate 14.9 umol/l (4.0–11.0), 17-OH Progesterone 7.6 nmol/l (0.6&#15...

ea0059p041 | Bone and calcium | SFEBES2018

Management of osteogenesis imperfecta in adulthood – a single centre experience

Dar Shujah , Khalily Naveed , Khan Shakib , Kamwa Vicky , Cole Trevor , Ayuk John , Gittoes Neil , Hassan-Smith Zaki

Introduction: Osteogenesis imperfecta (OI) is a genetic, heterogeneous, connective tissue disorder most commonly caused by mutations in type I collagen genes. A hallmark of disease is frequent fractures that are precipitated by minimal trauma. There are limited data on the impact of OI on non-skeletal outcomes across the lifecourse. We present cross-sectional data of one of the largest single centre patient cohorts of OI in adulthood (n=186).The aim of this study was ...