Endocrine Abstracts

Background: Maturity-onset diabetes of the young (MODY) is a group of 13 monogenic forms of diabetes transmitted in an autosomal dominant pattern and is characterized by a primary defect in pancreatic β-cell function. This disease has an early onset, usually before 25 years of age. It may present with mild asymptomatic hyperglycemia with progressive development to clinical diabetes mellitus. First-line treatment relies on sulphonylureas or insulin according to MODY subtyp...

The prevalence of Metabolic Associated Steatotic Liver Disease (MASLD) is approximately 55% in patients with Type 2 diabetes (T2DM). The EASL-EASD-EASO guidelines recommend screening patients with T2DM for MASLD. Fibrosis-4 Index (FIB-4) is a simple tool used to screen for MASLD in T2DM. FIB-4 scores are characterised as; low (<1.3), moderate (1.3 – 2.67) or high risk (>2.67). The aim of the audit was to screen a consecutive number of patients attending the out-pa...