ea0059p041 | Bone and calcium | SFEBES2018
Dar Shujah
, Khalily Naveed
, Khan Shakib
, Kamwa Vicky
, Cole Trevor
, Ayuk John
, Gittoes Neil
, Hassan-Smith Zaki
Introduction: Osteogenesis imperfecta (OI) is a genetic, heterogeneous, connective tissue disorder most commonly caused by mutations in type I collagen genes. A hallmark of disease is frequent fractures that are precipitated by minimal trauma. There are limited data on the impact of OI on non-skeletal outcomes across the lifecourse. We present cross-sectional data of one of the largest single centre patient cohorts of OI in adulthood (n=186).The aim of this study was ...