Endocrine Abstracts

The project study thyroid diseases which are common endocrine pathology in Uzbekistan appearing in women of reproductive age. We study thyroid hormones, since its close relation with the female reproductive hormones (estrogen and progesterone), ensure the normal functioning of the ovaries and the maturation of the eggs or its disorder. The study evaluated thyroid dysfunction – such as thyrotoxicosis or hypothyroidism – that might lead to an imbalance of reproductive ...

The purpose of the study was to study the characteristics of the course of pregnancy and childbirth in women with prolactinomas, as well as the effect of pregnancy on the size and functional activity of prolactin-secreting pituitary adenomas.Materials and methods: 70 women with prolactinomas during pregnancy were examined. The age of the examined patients from 20 to 38 years (28.9 ± 0.5 years). The duration of the disease ranged from 3 months to 20 ...

Menstrual disorders pose a huge burden on gynecology OPD, accounting for approximately 20% of attendance Thyroid hormones play an important role in reproductive function by direct effects on ovaries and indirectly influencing on sex hormone-binding globulin. Thyroid impairment can cause menstrual irregularities and infertility. In India, thyroid disorders are most common endocrine diseases. Thyroid disorders manifestation increases with age, and approximately 26% of premenopau...

Keywords: Reproductive system of women who have had coronavirus, Covid-19, women. The relevance of the problem. Currently, there are no published evidence-based recommendations for the management of women who have undergone COVID-19. According to statistics, women carry COVID-19 more easily than men, and the likely consequences of this coronavirus infection for reproductive health cannot be ignored. It is necessary not only to carefully monitor the respiratory parameters of pa...

The purpose of the study was to assess the functional state of the kidneys in patients with type 2 diabetes, depending on hypoglycemic therapy.Material and research methods: 60 patients with type 2 diabetes with CKD. The mean age of the patients was 54±2.5 years, the experience of diabetes was 11.7±0.18, the mean Hb1C was 9.1%, and the mean fasting glycemia was 11.2 mmol/l. The patients were divided into 2 groups: group 1-30 patients on the iSG...

Relevance: Prolactinoma is an adenoma of the pituitary gland with the production and secretion of prolactin (PRL) in varying degrees, almost always benign, but, nevertheless, often clinically significant and causing difficulties in treatment. Often prolactinomas are classified according to size as microadenomas (less than 10 mm in diameter) or macroadenomas (more than 10 mm in diameter). More than 90% of prolactinomas are small, intrasellar tumors that rarely increase in size....

Aim of the research: To study relationship between GH levels and acromegaly complications development in different therapy approaches.Patients and methods: We evaluated 50 patients with GH secreting adenomas referred to CCSSE from 1999 to 2004. Age of patients was from 19 to 63 years-old (mean age 40±19 years-old). Duration of the disease was from 1 to 23 years.Methods: Clinical and biochemical tests of neurological status; RI...

Aim of the research: To study clinical and epidemiologic features of acromegaly in the Republic of Uzbekistan.Patients and methods: We observed acromegalic patients registered from 2007 to 2009 who are dispensarized in the regions of the country. Of the 369 patients 143 were males (38.7%) and 226 females (61.3%). Mean age of the patients was 42.6 years-old. Duration of the disease varied from 1 to 31 years.Results: According to the...

Aim of the research: To study the rate of vascular complications in acromegaly in the Republic of Uzbekistan.Patients and methods: We observed acromegalic patients registered from 2007 to 2009 who are dispensarized in the regions of the country. Of the 369 patients 143 were males (38.7%) and 226 females (61.3%). Mean age of the patients was 42.6 years-old. Duration of the disease varied from 1 to 31 years.Results: We assessed the r...

Aim of the research: To study long and short-term therapy effectiveness with dopamine agonists in acromegaly.Patients and methods: Three hundred and sixty-nine patients with acromegaly registered by December, 1 2009 in the Republic of Uzbekistan. Of these patients we observed 20 cases with GH-secreting pituitary adenoma. Age of the patients was from 19 to 63 years-old (mean age 40±19 years-old), duration of the disease was from 1 to 23 years. Patien...