Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1141 | Female Reproduction | ECE2017

Epigenetics of female hypogonadotropic hypogonadism: analysis of mRNA expression of engaged in IHH genes

Loktionova Anna , Ilovayskaya Irena , Eneva Natela , Khusniyarova Karina , Nefedova Lidia , Kim Alexander , Dreval Alexander

Hypogonadotropic hypogonadism is a syndrome which may be manifested clinically by low sex steroids because of low (or inappropriately normal) gonadotropins. To date, more than 30 genes were reported as possible reason for this condition, but genetic basis is still unknown for ~60% of HH cases. Due to this fact we decided to analyze mRNA expression of several HH-related genes which can be found in leukocytes of peripheral blood: GNRHR and GNRH1 (which are necessary for adequate...