Searchable abstracts of presentations at key conferences in endocrinology

ea0014s11.1 | Polycystic ovary syndrome | ECE2007

The CAG repeat polymorphism of the androgen receptor gene is an independent risk factor for polycystic ovary syndrome (PCOS)

Schuering Andreas , Jurgens Andrea , Gromoll Jorg , Zitzmann Michael , Sonntag Barbara , Nieschlag Eberhard , Greb Robert , Kiesel Ludwig

Introduction: Polycystic ovary syndrome (PCOS) is a frequent disorder with a variable phenotype and a suspected genetic background. Androgenic effects constitute the central mechanism for the clinical, biochemical and sonographic features of PCOS. Androgenic effects are transported by the androgen receptor, whose activity can be modulated by a genetic polymorphism. We investigated the role of the CAG repeat polymorphism of the androgen receptor in PCOS.P...