Searchable abstracts of presentations at key conferences in endocrinology

ea0013p122 | Cytokines and growth factors | SFEBES2007

Interleukin-1alpha: the key to polycystic ovarian syndrome?

Sathyapalan Thozhukat , Speirs Valerie , Killick Stephen , Atkin Stephen L

Polycystic ovary syndrome (PCOS) affects 5–10% of reproductive-aged women and is associated with hyperandrogenism and chronic anovulation. Leukocytes, together with granulosa cells, may contribute to the pathogenesis of PCOS via their ability to secrete an array of cytokines implicated in follicle growth.Aim: Using RT-PCR, we screened for the expression of a range of cytokines in ovarian biopsies obtained from PCOS patients and normal individuals to...