Searchable abstracts of presentations at key conferences in endocrinology

Endocrine Abstracts

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ea0050apw1.1 | Tissue Engineering for Regenerative Medicine in Endocrinology | SFEBES2017

Reprogramming gastric tissues for insulin production

Ariyachet Chaiyaboot , Lu Jiaqi , Kim Hyunkee , Zhou Qiao

Generating functional insulin-secreting cells is a major goal of developing cell therapies for diabetes. Studies have shown that insulin+ cells can be derived from non-beta cells by cellular reprogramming. We carried out a genetic screen in mouse to identify adult cell types amenable for direct conversion to insulin+ cells by a cocktail of reprogramming factors (Ngn3, Pdx1, and Mafa, termed NPM factors). Surprisingly, the antral stomach epithelial cells w...
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ea0050apw1.1 | Tissue Engineering for Regenerative Medicine in Endocrinology | SFEBES2017

Reprogramming gastric tissues for insulin production

Ariyachet Chaiyaboot , Lu Jiaqi , Kim Hyunkee , Zhou Qiao

Generating functional insulin-secreting cells is a major goal of developing cell therapies for diabetes. Studies have shown that insulin+ cells can be derived from non-beta cells by cellular reprogramming. We carried out a genetic screen in mouse to identify adult cell types amenable for direct conversion to insulin+ cells by a cocktail of reprogramming factors (Ngn3, Pdx1, and Mafa, termed NPM factors). Surprisingly, the antral stomach epithelial cells w...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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