Endocrine Abstracts

Objective: The efficacy of mineralocorticoid receptor (MR) antagonists has been demonstrated in MR-related hypertension, including primary aldosteronism (PA). Non-inferiority in 24-hour blood pressure reduction has been shown for esaxerenone 2.5 mg/day compared to eplerenone 50 mg/day in patients with essential hypertension. However, no trial has compared the antihypertensive effects of these drugs in patients with PA. This study aimed to investigate the effect of switching fr...

Introduction: Acromegaly hardly complicates hypercortisolemia due to co-over-secretion of ACTH from the pituitary tumor. Herein, we present a case of acromegaly with hypercortisolemia.Clinical case: A 68-year-old woman visited a local clinic due to bitemporal visual field defects. A magnetic resonance imaging scan of the pituitary gland showed a 25 mm-sized mass extending from the sellar to the suprasellar region, and she was referred to our hospital for...