Endocrine Abstracts

Oestradiol-17β regulates diverse tissues and cells, both within and outside the reproductive system including human cancer cells. Currently used ERs agonists or antagonists are synthetic compounds prepared by structure modifications. Alternatively, peptide mimics of steroids would allow preparation of biased combinatorial libraries of chemical and biological origin, from which estrogenic peptides with tissue selective profiles can be selected. The phage-display peptide li...