Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps2-19-08 | Thyroid Hormone Transport & Metabolism Basic | ETA2023

Thyroglobulin detection in extracellular vesicles isolated from human plasma

Đorić Ilona , Janković Miljuš Jelena , Kosanović Maja , Išić Denčić Tijana , Živaljević Vladan , Selemetjev Sonja

Objective: Detecting recurrence of differentiated thyroid cancer is performed by serial measurements of serum thyroglobulin (Tg) levels, however, in the presence of anti-Tg antibodies, this measurement is unreliable. Extracellular vesicles (EVs) are small membrane-enclosed structures, with a prominent role in cell-to-cell communication. All cell types release EVs and they can be isolated from various biofluids, while their cargo reflects the content of the cell of origin. Prev...