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ea0037gp.10.06 | Calcium, Vitamin D and Bone | ECE2015

The (CAG)n repeat polymorphism of the androgen receptor gene is associated with bone mineral density in menopausal women

Markatseli Anastasia , Lazaros Leandros , Kostoulas Harilaos , Markoula Sofia , Tigas Stelios , Georgiou Ioannis , Tsatsoulis Agathocles

Introduction: Osteoporosis is a systemic skeletal disease with a strong genetic component. The androgen receptor (AR) is encoded by the AR gene and mediates the action of androgens, which play an important role in bone metabolism. Polymorphisms in the AR gene may be implicated in the pathogenesis of osteoporosis.Objectives: The present study aimed to explore the influence of the (CAG)n repeat polymorphism of AR</em...

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ePoster

ea0032p89 | Bone and Osteoporosis | ECE2013

Association of the (TTTA)n repeat polymorphism of CYP19 gene with bone mineral density in Greek peri- and postmenopausal women

Markatseli Anastasia , Lazaros Leandros , Kostoulas Harilaos , Sakaloglou Prodromos , Markoula Sofia , Tigas Stelios , Georgiou Ioannis , Tsatsoulis Agathocles

Introduction: Aromatase is encoded by the CYP19 gene and catalyzes the conversion of androgens to estrogens, which in turn regulate skeletal homeostasis. Polymorphisms in the CYP19 gene have been studied for their association with bone mineral density (BMD) in the general population with mixed results.Objectives: To explore the influence of the CYP19 (TTTA)n repeat polymorphism on BMD and serum levels of osteoprotegerin (OPG), receptor activator...

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Endocrine Abstracts

The (CAG)n repeat polymorphism of the androgen receptor gene is associated with bone mineral density in menopausal women

Association of the (TTTA)n repeat polymorphism of CYP19 gene with bone mineral density in Greek peri- and postmenopausal women

BiosciAbstracts