Endocrine Abstracts

Aim: To present a case of severe primary hyperparathyroidism (PHPT) manifested predominantly with polyuria.Case: A 53 years old caucasian female presented to the emergency room with polyuria (5-6 l), and increasing during last 4 weeks dehydration, weight loss (10 kg), weakness, confusion. Diabetes mellitus and insipidus had been excluded. After hypercalcemia (3.6–3.9 mmol\l), Ca++ to 2.0 mmol\l and PTH of 616 pg\ml (11–62) were revealed acute P...

Introduction: Achievement of stable normocalcemia (88–98.8%) is considered a criterium of efficiency of surgical operations for primary hyperparathyroidism (PHPT) (P.Goudet et al. 2001, Zeiger 1997). In 1–15% of cases, persistence of PHPT is noted (Mariani et al. 2003, Mariette et al. 1998).Description of methods: In 110 of 175 patients (aged 14–72 years), parathyroid adenoma was verified, in 57 – hyperplasi...

From 1987 to 2008, 226 patients were operated on for primary hyperparathyroidism (pHPT). In 17 (men and women, aged 21–71 years) of them, parathyroid carcinoma (PC) was verified by histologic analysis. Mixed pHPT form was noted in 12 patients, visceropathic one – in 4, and asymptomatic – in 1. Hypercalcemia was revealed in 14 of 17 patients, and elevation of parathyroid hormone (PTH) level (426–1160 pg/ml) – in 12. In 5 patients operated on before 1990...