Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep158 | Calcium and Vitamin D metabolism | ECE2016

Investigation of interference with binding proteins in two commonly used 25-hydroxyvitamin D assays

Toldy Erzsebet , Viragh Eva , Horvath Dora Eszter , Kovacs Laszlo , Kovacs Eniko Andrea , Lakatos Peter , Locsei Zoltan

Background: Adequate vitamin D supply is necessary for bone metabolism and also for the general maintenance of health. 25OHD is transported primarily bound to vitamin-D binding protein (DBP), but also to albumin. Lower concentration of plasma proteins may cause difficulties in immunoanalytics. Our aim was to investigate the protein dependence of the two most often used 25OHD immuno- (CLIA) and protein binding- (ECLPBA) assays.Methods: levels were measure...