ea0035p20 | Adrenal cortex | ECE2014
, Montsko Gergely
, Mezosi Emese
, Kovacs Gabor L
Cortisol is a glucocorticoid hormone with low molecular weight (362 Da) synthesized from cholesterol in the adrenal gland. The release is regulated by the hypothalamicpituitary-adrenal (HPA) axis. Approximately 95% of the circulating amount is bound to proteins (CBG and albumin), but only the remaining free fraction is biologically active. Serum cortisol level is routinely analysed in laboratory medicine, though the widespread immunoassays (RIA and ECLIA) have the disadv...