Searchable abstracts of presentations at key conferences in endocrinology

ea0041ep158 | Calcium and Vitamin D metabolism | ECE2016

Investigation of interference with binding proteins in two commonly used 25-hydroxyvitamin D assays

Toldy Erzsebet , Viragh Eva , Horvath Dora Eszter , Kovacs Laszlo , Kovacs Eniko Andrea , Lakatos Peter , Locsei Zoltan

Background: Adequate vitamin D supply is necessary for bone metabolism and also for the general maintenance of health. 25OHD is transported primarily bound to vitamin-D binding protein (DBP), but also to albumin. Lower concentration of plasma proteins may cause difficulties in immunoanalytics. Our aim was to investigate the protein dependence of the two most often used 25OHD immuno- (CLIA) and protein binding- (ECLPBA) assays.Methods: levels were measure...

ea0084ps3-14-123 | Thyroid Cancer CLINICAL 2 | ETA2022

A case of warthin-like papillary thyroid cancer. surgical decision based on eu-tirads criteria

Laszlo Kovacs Gabor , Vass Laszlo , Csapo Zsolt , Solymosi Tamas

Introduction: The Warthin-like variant of papillary thyroid cancer (WLPTC) is a rare subtype of papillary thyroid carcinoma (PTC) resembling Warthin tumours of the salivary glands, and more commonly associated with Hashimoto’s thyroiditis than other types of PTCs. The WLPTC is characterized by papillae lined by large oncocytic cells with cores having dense lymphoplasmacytic infiltrate. The prognosis of WLPTC is the same or less aggressive than that of classical PTC, but i...

ea0049gp44 | Bone & Calcium Homeostasis 2 | ECE2017

Investigation of total and free 25OHD vitamin levels in patients with chronic renal failure on different dose of cholecalciferol

Toldy Erzsebet , Kovacs Laszlo , Nemeth Reka , Szakacs Gyulane , Kulcsar Imre , Locsei Zoltan

The total 25-hydroxy-vitamin-D (t-25OHD) level reflects the vitamin-D supply, but it is also influenced by the levels of vitamin-D-binding-proteins (DBP) and albumin. The type of dialysis influences the levels of serum proteins. The ‘free-hormone hypothesis’ states that only the free molecules (f25OHD) can diffuse intracellular. Our aim was to evaluate the total, calculated (c-f25OHD) and direct measured (dm-f25OHD) 25OHD levels in patients with chronic renal disease...

ea0037ep135 | Reproduction, endocrine disruptors and signalling | ECE2015

NMDA receptor mediated limbic encephalitis in a woman with mature cystic ovarian teratoma: a case report

Vanya Melinda , Kovacs Zoltan , Gorgoraptis Nikos , Salek-Haddadi Afram , Kovacs Laszlo , Bartfai Gyorgy

Objective: Our aim was to present a case of paraneoplastic NMDA-R antibody-mediated limbic encephalitis in a woman with OT thereby providing information facilitating diagnosis of OT in women, who present with symptoms of paraneoplastic limbic encephalitis (LE) for obstetricians and gynaecologists with appropriate.Case: We report the case of a 25-year-old women, who developed NMDA-R-antibody mediated autoimmune encephalitis and who displayed confusion, di...

ea0032p113 | Calcium and Vitamin D metabolism | ECE2013

Evaluation of two routinely used 25OHD assays and serum variables in patients on dialyses

Locsei Zoltan , Kovacs Laszlo , Balogh Dora , Szijarto Adrienn , Kalman Bernadette , Kovacs Gabor L , Toldy Erzsebet

The total 25-hydoxy-vitamin-D (t25OHD) level can be assessed by various methods and reflects vitamin D intake. Results are influenced by the serum variables affected by dialyses.Aims: To examine t25OHD and bioavailable vitamin D (b25OHD) by two methods in patients on peritoneal-(PD) and hemodialysis (HD).Methods: We studied 37 HD (64±15 years) and 36 PD (63±18 years) patients. The t25OHD was assessed by chemiluminescence ...

ea0022p188 | Clinical case reports and clinical practice | ECE2010

Case report of Borrelia burgdorferi infection as a possible trigger of Riedel’s thyroiditis

Kovacs Gabor Laszlo , Szabolcs Istvan , Gorombey Zoltan , Kovacs Laszlo , Hubina Erika , Denes Judit , Goth Miklos

Background: The detectable levels of thyroid antibodies in patients suffering from Riedel’s chronic fibrosing thyroiditis (RT) suggest a link between RT and Hashimoto’s thyroiditis, but the pathogenesis of RT is not really known. Lyme disease is the most frequent tick-borne infection with variable manifestations in different organs caused by Borrelia burgdorferi (Bb).Case report: A 59-year-old woman presented in our outpatient clinic wit...