Endocrine Abstracts

Background: Obesity in pregnancy is associated with hyperinsulinemia, impaired endothelial function, inflammatory up-regulation and higher risk of placental pathological lesions. However not all obese individuals demonstrate similar metabolic profiles. The present study was designed to investigate placental histopathology in lesions that are associated with maternal and fetal circulation abnormalities, in nonobese and obese women with and without metabolic alterations.<p c...