ea0070aep25 | Adrenal and Cardiovascular Endocrinology | ECE2020
Caratti Giorgio
, Stifel Ulrich
, Kozak Bozhena
, Rauch Alexander
, Tuckermann Jan
Insulin resistance and obesity are a global health problem and directly linked to macrophage-driven inflammation of the adipose tissue. Glucocorticoid therapy, used to treat inflammatory conditions, increases adiposity and insulin resistance. It is unknown however, whether anti-inflammatory actions of glucocorticoids at physiological levels can have beneficial effects on adipose tissue inflammation, potentially limiting insulin resistance. Using a macrophage specific deletion ...