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Endocrine Abstracts

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ea0070aep802 | Reproductive and Developmental Endocrinology | ECE2020

Pituitary response to GnRH stimulation in patients with secondary hypogonadism is modulated by different FSHB -211 G/T genotypes

Sansone Andrea , Schubert Maria , Tüttelmann Frank , Zitzmann Michael , Krallmann Claudia , Kliesch Sabine , Gromoll Jörg

Background: The FSHB –211 G > T single nucleotide polymorphism (SNP) is known to affect pituitary FSH output by reducing the transcriptional activity of FSHB. Identifying the response of the pituitary to exogenous GnRH stimulation in subjects with FSHB -211 G > T SNP could provide useful information concerning the mechanisms regulating FSH synthesis and release.Objectives: This study aimed to assess the pituitary...
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Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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