Searchable abstracts of presentations at key conferences in endocrinology

ea0014oc5.7 | Thyroid basic | ECE2007

The 1188A/C polymorphism of IL-12 gene in Graves’ disease

Wawrusiewicz-Kurylonek Natalia , Gorska Maria , Mysliwiec Janusz , Kretowski Adam Jacek

Background and aims: Interleukin-12 (IL-12) is a pro inflammatory cytokine, which was suggested to play a key role in the pathogenesis of Th1-cell-mediated autoimmune diseases. The aim of our study was to estimate the association of 1188A/C polymorphism of IL12B gene with the predisposition to GravesÂ’ disease (GD) in Polish population.Materials and methods: The study was performed in the group consisting of 245 individuals with GD sequentially recru...