Searchable abstracts of presentations at key conferences in endocrinology

ea0016p433 | Neuroendocrinology | ECE2008

Unusual pattern of pituitary insufficiencies following traumatic brain injury evaluated by insulin tolerance test

Faust Michael , Wille Julia , Schumann Christina , Lippert-Gruener Marcela , Ernestus Ralf I , Krone Wilhelm

There is growing evidence that pituitary failure is a common complication of traumatic brain injury. However, prevalence of hypopituitarism following traumatic brain injury varies between 25 and 69% in the literature. Moreover, the pattern of involved hypothalamic/pituitary axes differs considerably in the published trials. This might be due to small and inhomogeneous series of patients and different test methods in previous studies. The aim of our study was therefore to inves...

ea0014oc6.5 | Cardiovascular endocrinology | ECE2007

Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression in mononuclear blood cells: a randomized trial in healthy men

Gouni-Berthold Ioanna , Berthold Heiner , Gylling Helena , Ko Yon , Plat Jogchum , Krone Wilhelm

Context: Ezetimibe and simvastatin are often used in combination to lower blood lipid levels. The consequences of this combination at the molecular level are unknown.Objective: To examine their effects on the LDL receptor (LDLR) protein expression and on the LDLR and HMG-CoA reductase gene expression in peripheral blood mononuclear cells (PBMC).Design, setting and participants: Prospective, randomized, parallel 3-group trial. Twent...