Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep43 | Adrenal cortex (to include Cushing's) | ECE2017

A case of recurrent Cushing’s disease after total bilateral adrenalectomy

Vicic Ivan , Kruljac Ivan , Cacic Miroslav , Peric Bozidar , Filipovic-Grcic Maja , Mirosevic Gorana , Cerina Vatroslav , Pazanin Leo , Vrkljan Milan

Bilateral adrenalectomy usually results in lifelong primary adrenal insufficiency. Evidence exists that up to 34% of patients with CushingÂ’s disease (CD) have some degree of endogenous cortisol secretion after bilateral adrenalectomy due to ACTH driven hyperplasia of residual cortical tissue. We present a case of a patient with atypical corticotropinoma/carcinoma and recurrence of CD after bilateral adrenalectomy.A 59-year-old man presented with Cus...

ea0049ep172 | Endocrine tumours and neoplasia | ECE2017

A nomogram consisted of routine biochemical tests may increase the diagnostic accuracy of chromogranin A in detecting patients with neuroendocrine tumors

Vurnek Ivan , Kruljac Ivan , Ćaćić Miroslav , Perić Božidar , Filipović-Grčić Maja , Mirošević Gorana , Kust Davor , Vrkljan Milan

Introduction: Falsely elevated serum chromogranin A (CgA) is associated with the use of proton pump inhibitors, the presence of renal impairment and systemic inflammation. We aimed to investigate which laboratory parameters are independently associated with increased CgA and to develop a nomogram, in order to improve the diagnostic accuracy of CgA in detecting patients with neuroendocrine tumors (NET).Methods: Our retrospective study included 155 subject...

ea0026p595 | Clinical case reports | ECE2011

A unique case of multifocal intrathyroid parathyroid carcinoma

Kruljac Ivan , Sulentic Petra , Cigrovski Maja Berkovic , Mahecic Davorka Herman , Mirosevic Gorana , Ivkic Mirko , Vrkljan Milan

Intrathyroidally located parathyroid carcinoma is extremely rare cause of primary hyperparathyroidism. Multifocal papillary and follicular thyroid carcinomas are rather common.We report a case of 40-year old man presenting with substantial weight loss, anemia and multiple osteolytic lesions of both tibias. Peak serum calcium level was 5.0 mmol/l, parathyroid hormone (PTH) level was 989 pg/ml. Left thyroid lobe was firm and enlarged. Routine percutaneous ...

ea0026p214 | Pituitary | ECE2011

Multimodal treatment and minimally invasive surgery for 117 pituitary adenomas: a Croatian Pituitary Centre experience

Kruljac Ivan , Maric Andreja , Sulentic Petra , Cigrovski Maja Berkovic , Mahecic Davorka Herman , Mirosevic Gorana , Kastelan Darko , Vrkljan Milan

Studies that consolidate the results of medicamentous and surgical treatment of pituitary adenomas are scarce. Pure endoscopic endonasal transsphenoidal surgery is rather new technique.The aim of this study is to report on early postoperative outcome of pure endoscopic endonasal transsphenoidal surgery and to present the results of multimodal treatment in patients with postsurgical failure.We reviewed 117 consecutive patients who u...

ea0049ep463 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Incidence of diabetic ketosis and ketoacidosis in Caucasian adults with type 2 diabetes mellitus: a population-based study

Ćaćić Petra , Kruljac Ivan , Ćaćić Miroslav , Perić Božidar , Filipović-Grčić Maja , Mirošević Gorana , Vrkljan Milan

Aims: Diabetic ketosis (DK) and diabetic ketoacidosis (DKA) are known complications of type 1 diabetes mellitus (T1DM). However, DK and DKA have been described in T2DM. Referred to as ketosis-prone T2DM, this subtype of T2DM has been described in Hispanics and Afro-Americans of sub-Saharan Africa, but the incidence and pathogenesis remains unknown. We aimed to analyze characteristics of patients with diabetic ketosis (DK) and diabetic ketoacidosis (DKA) in Ca...

ea0049ep549 | Diabetes complications | ECE2017

Prognostic factors and all-cause mortality in patients with type 2 diabetes presenting with diabetic ketoacidosis: a population based, case-control study

Ćaćić Petra , Ćaćić Miroslav , Kruljac Ivan , Perić Božidar , Filipović-Grčić Maja , Mirošević Gorana , Vrkljan Milan

Introduction: Little is known about diabetic ketoacidosis (DKA) in type 2 diabetes mellitus (T2DM). Moreover, the clinical impact of diabetic ketosis (DK) in T2DM is elusive. The aim of this study was to analyze characteristics and mortality of patients with DKA and DK and to identify possible prognostic factors.Methods: This was a population-based, cross-sectional study that included all patients with T2DM presenting to emergency department with DKA, ov...