Endocrine Abstracts

Thyrotoxic periodic paralysis (TPP) is due to a fall in potassium levels and threat life if it effects respiratory muscles. Men are more effected than women, and lower extremeties are more prone to involvement. Serum potassium in hyperthroidism is usually normal, but Na+/K+ ATP’ase sensitivity is increased and extracellular potassium rapidly passes to the intracellular space. Beta blockers, small dose potassium replacement and hyperthyroidism treatme...

Purpose: Thyroid cancer is the most common cancer of endocrine system. Osteopontin (OPN) is a secreted glycoprotein that has a role in osteoblast differentiation and bone formation. Osteopontin has other roles in cell migration and cell survival and its related to tumorigenesis and cell invasion. Osteopontin levels have been determined higher in some malignancies. The purpose of this study is to determine plasma osteopontin levels in patients with new onset diagnosed thyroid c...

A male patient aged 63 years old was admitted to the emergency department with the complaints of polydipsia, polyurea and dizziness. He had hypertension which was on a calcium channel blocker and his hypertension was in control. His plasma glucose was measured as 564 mg/dl and hospitalized due to his new onset diabetes. His family history showed that, his mother, uncle, aunt and all six brothers were diagnosed as diabetes mellitus. His uncle, aunt and aunts children were using...

Aim: Differentiated thyroid cancer (DTC) is the most commonly seen endocrinological tumour. During the follow up of DTC, serum thyroglobulin (TG) levels, neck ultrasound, fine needle aspiration biopsy (FNAB) of the suspicious lymph nodes are important tools. TG washout of the suspicious lymph node as well as the FNAB can detect metastasis and recurrences earlier. In this study we aimed to show the diagnostic role of TG washout of suspicious lymph node FNAB which is not routine...

Introduction: Thyroid gland is susceptible for nodulation. It is not clear which mechanism is responsible for the growth of only some follicular cells resulting in nodule formation. Selenium deficiency may a risk factor in the development of thyroid nodules. The aim of this study was to investigate the relationship between selenium levels in patients with euthyroid nodular thyroid diseases.Design: Euthyroid 70 patients with solitary thyroid nodule, euthy...

Aim: Differentiated thyroid carcinomas (DTC) composes 95% of all thyroid malignancies originating from thyroid follicular epithelial cells. DTC expresses TSH receptors so long time TSH stimulation may cause cancer occurrence or malignancy progression. So we aimed to assess the role of TSH levels in predicting thyroid cancer stage or aggressiveness.Methods: We retsopectively searched thyroid cancer patients fort he last 10 years in our instution. Totally ...

Introduction: Adrenal incidentelomas are new era of the endocrinology. We aimed to see the results of adrenal masses retrospectively.Methods: Patients admitted to the Internal Medicine outpatient clinic for different complaints were retrospectively evaluated. Patients whom abdominal imaging like ultrasonography, magnetic resonance imaging or computed tomography were done and incedentally established adrenal masses were evaluated. Patients with a history ...

Methods: This study, was a cross-sectional survey. Sampling design was based upon multistage probability sampling. Patient with diabetes, hypertension, cardiovascular diseases and any other diseases were excluded from the study. Age and gender were noted. Heights, weights and waist circumference (WC) were measured. BMI was calculated. Blood pressure (BP) was measured. Fasting thyrigliseride levels were evaluated. Patients were divided into two groups according to their triglyc...

Introduction: Differentiated thyroid cancer has usually good prognosis and long-term survival. Distant metastasis ratio is 5–15%. Metastasis to cerebrum, breast, liver, kidney, muscle, and skin is relatively rare. The study of molecular mechanisms of PTC has demonstrated that BRAFV600E gene mutation is a significant event in the process of this disease.Case: 55-year-old-male patient who had multinodular goiter showed malignant cytology in fine-needl...

Introduction: Primary hyperparathyroidism (PHP), is generalized with calcium, phosphate, and bone metabolism disorder due to increased PTH secretion. It’s common in fifth and sixth decades. Nowadays, it’s widely detected by measurement of blood calcium and may be presented with minimal or no symptoms.Design: 102 patients with PHP admitted to Department of Endocrinology, between years of 2008–2013 were analyzed.Result...