Searchable abstracts of presentations at key conferences in endocrinology

ea0085oc8.1 | Oral Communications 8 | BSPED2022

Do we need earlier thyroid surveillance amongst PTEN patients in the UK?

Kaninde Abhidhamma , Kuo Michael , Ren Ong Kai , Barrett Timothy , Dias Renuka

Background: Germline mutations in the Phosphatase and Tensin Homolog Hamartoma tumour (PTEN) gene are associated with a number of conditions, collectively known as PTEN hamartoma tumour syndromes (PHTS). Individuals with PHTS are at increased risk of a number of cancers primarily in adulthood including differentiated thyroid carcinoma (DTC) with an estimated lifetime risk of DTC of up to 38%. International guidance recommends screening commencing from 17 years while the 2017-U...