Searchable abstracts of presentations at key conferences in endocrinology

ea0014p160 | (1) | ECE2007

Inhibitory effect of rosiglitazone – PPARgamma receptor ligand on growth of human adrenocortical tumor cells in vitro

Winczyk Katarzyna , Lawnicka Hanna , Fuss-Chmielewska Julita , Kolomecki Krzysztof , Kuroszczyk Jacek , Pawlikowski Marek

Introduction: The peroxisome proliferator-activated receptors gamma (PPARγ) are nuclear receptors which are detected in normal and pathological tissues. Our earlier study showed the overexpression of PPARγ in human adrenal tumors and pituitary adenomas in comparison to normal glands. The in vitro experiments indicated that ligands of PPARγ inhibit growth of many tumors including pituitary adenomas, thyroid cancers and adrenal carcinomas. However, the data...