Searchable abstracts of presentations at key conferences in endocrinology

ea0022p511 | Growth factors | ECE2010

IGF1 and IGFBP3 levels in relapsing-remitting and secondary progressive multiple sclerosis (MP)

Di Somma Carolina , Lanzillo Roberta , Savanelli Maria Cristina , Scarano Elisabetta , Contaldi Paola , Lombardi Gaetano , Morra Vincenzo Brescia , Colao Annamaria

Background: There is a growing body of evidence of an alteration in GH/IGF1 axis in neurological diseases. IGF1 and IGFBP3 serum levels are reported to be similar in controls, relapsing remitting (RR) MS and primary progressive (PP) MS patients, but in RR patients on IFN therapy they were found to be higher then in controls. IGFBP3 was found to correlate to progression index in PPMS.Objective: To compare IGF1 and IGFBP3 serum levels in RR MS and secondar...