Endocrine Abstracts

Aim: To assess the thyroid and reproductive system status in 222 women with normal menstrual cycles.Material and Methods: Patients were referred for thyroid ultrasonography and concurrent breast ultrasonography. The 160 women were divided into two groups, based on the nature of the thyroid pathology.Results: The 1st group included 90 women with autoimmune thyroiditis (AIT), the median age was 36.00 [25.00; 50.00] years, the 2nd gro...

Multiple endocrine neoplasia type 2 (MEN2) is a rare hereditary autosomal dominant syndrome, caused by activating germline mutations in the RET proto-oncogene. Medullary thyroid carcinoma (MTC) remains the most common and aggressive manifestation of MEN2. The family case of MEN 2 syndrome in Belarussian population is analyzed. During the analysis of the records of clinical case of patient’s death in the reginal hospital because of thrombosis of mesenteric vessels and acut...

Introduction/Aim: The incidence of type 2 diabetes in Belarus continues to grow. Alongside with the standard treatment search for the new methods of intervention still continued. Whole body cryotherapy appears to be a promising method of metabolic correction. Study aim was the estimation of various low-temperature regimen influence on biochemical parameters and BMI characteristics of patients with metabolic syndrome and type 2 diabetes and selection the optimal low-temperature...

Androgen insensitivity leads to a defect of virilization in karyotypic males despite supraphysiologic androgen levels. Because of an impaired regulatory mechanism of the gonadotropin-androgen axis, both LH and T in serum may be elevated, leading to a distinctively high value of the LH×T multiplication product, which has been termed as the androgen sensitivity index (ASI). The aim of our present study was to investigate a cohort of young males with light decrease in penile...

Aim: To investigate the impact of overall obesity (Ob) and diabetes mellitus type 2 (DM2) on arterial stiffness and degree of insulin resistance in patients with arterial hypertension (AH) and abdominal Ob (AOb).Design and method: 74 subjects were divided according to presence of AH, AOb, Ob, and DM2 without insulin therapy. Control group 1 consisted of 26 subjects without AH, AOb, Ob, and DM2. All patients with AH were also diagnosed with AOb and amount...

Backgrounds and aim: Epidemiologic evidence suggests that people with diabetes are at significantly higher risk for many forms of cancer. The aim of the research was to identify cancer incidence distribution in Belarusian patients with type 2 diabetes mellitus.Methods: The study group included 73 patients: 46 (63%) women (mean age 65±8 years) and 27 (37%) men (70±7 years) with concurrent diabetes and cancer treated at Alexandrov National Cancer...

Introduction: To assess the effectiveness of treatment of obesity using complex integrated approach. In the treatment of obesity were used: instructions of patient in healthy eating habits, diet, taking medication that reduces fat absorption – lipid-adsorbent tablets, polyglucosamine (L112). Survey of patients was conducted. The received data were analysed.Description of methods: 61 obese patients (18 males and 43 females) were followed up for 12 we...

Pentoxifylline (PTX), a phosphodiesterase inhibitor, has a positive therapeutic effect in some autoimmune diseases due to immunomodulatory action.The aim of the study was to assess the influence of PTX on apoptosis and peripheral blood mononuclear cells (PBMC) proliferation in patients with Graves’ ophthalmopathy (GO).Twenty-four patients with GO and 32 healthy controls were investigated. GO patients were divided into two grou...