Searchable abstracts of presentations at key conferences in endocrinology

ea0070ep527 | Thyroid | ECE2020

Thyroid diseases and mastopathy

Vasyhina Irina , Danilova Larisa

Aim: To assess the thyroid and reproductive system status in 222 women with normal menstrual cycles.Material and Methods: Patients were referred for thyroid ultrasonography and concurrent breast ultrasonography. The 160 women were divided into two groups, based on the nature of the thyroid pathology.Results: The 1st group included 90 women with autoimmune thyroiditis (AIT), the median age was 36.00 [25.00; 50.00] years, the 2nd gro...

ea0063p829 | Adrenal and Neuroendocrine Tumours 3 | ECE2019

Multiple endocrine neoplasia type 2 family case in Belarussian population

Danilova Larisa , Grigorovitch Artur , Lushchyk Maxim

Multiple endocrine neoplasia type 2 (MEN2) is a rare hereditary autosomal dominant syndrome, caused by activating germline mutations in the RET proto-oncogene. Medullary thyroid carcinoma (MTC) remains the most common and aggressive manifestation of MEN2. The family case of MEN 2 syndrome in Belarussian population is analyzed. During the analysis of the records of clinical case of patient’s death in the reginal hospital because of thrombosis of mesenteric vessels and acut...

ea0063p930 | Diabetes, Obesity and Metabolism 3 | ECE2019

Whole body cryotherapy effect on weight gain and metabolic parameters of metabolic and type 2 diabetic patients

Lushchyk Maxim , Danilova Larisa , Tuzava Hanna , Dudzik Natallia , Zhauneryk Sviatlana

Introduction/Aim: The incidence of type 2 diabetes in Belarus continues to grow. Alongside with the standard treatment search for the new methods of intervention still continued. Whole body cryotherapy appears to be a promising method of metabolic correction. Study aim was the estimation of various low-temperature regimen influence on biochemical parameters and BMI characteristics of patients with metabolic syndrome and type 2 diabetes and selection the optimal low-temperature...

ea0020p676 | Steroid Receptors | ECE2009

Androgen insensitivity in the genesis of the mild penile size abnormalities in young belarussian men

Hlazkova Anastasiya , Danilova Larisa , Vashchula Viachaslau , Orlov Denis , Mitukova Tatsiana

Androgen insensitivity leads to a defect of virilization in karyotypic males despite supraphysiologic androgen levels. Because of an impaired regulatory mechanism of the gonadotropin-androgen axis, both LH and T in serum may be elevated, leading to a distinctively high value of the LH×T multiplication product, which has been termed as the androgen sensitivity index (ASI). The aim of our present study was to investigate a cohort of young males with light decrease in penile...

ea0037ep569 | Obesity and cardiovascular endocrinology | ECE2015

Effect of obesity and diabetes mellitus type 2 on vascular stiffness

Bourko Olga , Netchessova Tatiana , Bourko Irina , Danilova Larisa , Dashkevich Elena , Korolenko Galina

Aim: To investigate the impact of overall obesity (Ob) and diabetes mellitus type 2 (DM2) on arterial stiffness and degree of insulin resistance in patients with arterial hypertension (AH) and abdominal Ob (AOb).Design and method: 74 subjects were divided according to presence of AH, AOb, Ob, and DM2 without insulin therapy. Control group 1 consisted of 26 subjects without AH, AOb, Ob, and DM2. All patients with AH were also diagnosed with AOb and amount...

ea0037ep579 | Obesity and cardiovascular endocrinology | ECE2015

Malignant tumours in patients with type 2 diabetes mellitus and obesity

Shymanets Siarhei , Danilova Larisa , Lushchik Maxim , Dudarev Vyacheslav , Karman Andrey , Kharuzhyk Siarhei , Dovgalo Veronika

Backgrounds and aim: Epidemiologic evidence suggests that people with diabetes are at significantly higher risk for many forms of cancer. The aim of the research was to identify cancer incidence distribution in Belarusian patients with type 2 diabetes mellitus.Methods: The study group included 73 patients: 46 (63%) women (mean age 65±8 years) and 27 (37%) men (70±7 years) with concurrent diabetes and cancer treated at Alexandrov National Cancer...

ea0037ep601 | Obesity and cardiovascular endocrinology | ECE2015

The effectiveness of an integrated approach in the treatment of obesity

Bourko Irina , Lushchyk Maksim , Romanousky Aleksey , Isachkina Olga , Korolenko Galina , Kholodova Elena , Danilova Larisa

Introduction: To assess the effectiveness of treatment of obesity using complex integrated approach. In the treatment of obesity were used: instructions of patient in healthy eating habits, diet, taking medication that reduces fat absorption – lipid-adsorbent tablets, polyglucosamine (L112). Survey of patients was conducted. The received data were analysed.Description of methods: 61 obese patients (18 males and 43 females) were followed up for 12 we...

ea0020p61 | Thyroid | ECE2009

Influence of pentoxifylline on peripheral blood mononuclear cells proliferation and apoptosis in Graves’ ophthalmopathy

Melnik Irina , Hlazkova Anastasiya , Kosmacheva Svetlana , Goncharova Natallia , Danilova Larisa , Romanovskiy Aleksey

Pentoxifylline (PTX), a phosphodiesterase inhibitor, has a positive therapeutic effect in some autoimmune diseases due to immunomodulatory action.The aim of the study was to assess the influence of PTX on apoptosis and peripheral blood mononuclear cells (PBMC) proliferation in patients with Graves’ ophthalmopathy (GO).Twenty-four patients with GO and 32 healthy controls were investigated. GO patients were divided into two grou...