Searchable abstracts of presentations at key conferences in endocrinology

ea0081ep1000 | Thyroid | ECE2022

Assessment of thyroid function in healthy pregnant women living in iodine deficiency regions

Rybakova Anastasia , Platonova Nadezhda , Nikankina Larisa , Malysheva Natalia , Troshina Ekaterina

Background: During pregnancy, the physiology of the thyroid gland undergoes important changes. As a result, change levels of thyroid hormones. In the latest clinical guidelines, experts have recommended to perform population-based studies to determine reference intervals for thyroid hormones.Aim: To evaluate the reference intervals of free thyroxine in different trimesters of pregnancy in women living in regions with mild iodine deficiency.<p class="...

ea0090ep953 | Thyroid | ECE2023

COVID-19 – a trigger of autoimmune thyropathy disorders?

Kolpakova Evgeniia , Elfimova Alina , Nikankina Larisa , Troshina Ekaterina

Introduction: Research into autoimmune disorders associated with COVID-19 in the middle of an ongoing COVID-19 pandemic is an important and urgent challenge. We focus on the potential relationship between coronavirus infection and other autoimmune diseases, and the positive therapeutic effect of the treatment of severe forms of COVID-19 with drugs traditionally used in the treatment of rheumatological diseases. The results of this study are a starting point for understanding t...

ea0067o43 | Oral Presentations | EYES2019

Vitamin D deficiency in pregnant women in Russia Federation

Rybakova Anastasia , Platonova Nadezhda , Troshina Ekaterina , Nikankina Larisa

Pregnant women are at risk of developing diseases associated with deficiency of essential micronutrients.Objective: To assess the prevalence of vitamin D deficiency among pregnant women and its dependence on the trimester of pregnancy.Methods: We examined 476 pregnant women at different gestational periods from three regions of Russia (Moscow, Ivanovo, Smolensk). Concentration of 25(OH)vitamin D (ng/ml) was estimated by immunometri...

ea0063gp113 | Calcium and Bone 2 | ECE2019

Vertebral fracture in outpatients with type 2 diabetes mellitus

Yalochkina Tatiana , Tarbaeva Natalia , Rozhinskaya Liudmila , Nikankina Larisa , Belaya Zhanna

According to numerous studies, type 2 diabetes mellitus (T2DM) is associated with an increased risk of low traumatic non-vertebral fracture. There are a limited number of studies which evaluate lateral vertebral X-Rays in order to diagnose vertebral fractures in patients with T2DM. The goal of our study was to investigate the difference in vertebral fracture rate registered on lateral X-Ray between subjects with T2DM and a control group being under observation in the same outp...

ea0049ep685 | Obesity | ECE2017

Association of Transforming growth factor β and Fibroblast growth factor 21 with cardiovascular diseases in obese patients

Shvangiradze Teona , Troshina Ekaterina , Bondarenko Irina , Shestakova Marina , Nikankina Larisa

Introduction: Obesity and type 2 diabetes mellitus (T2DM) are associated with cardiovascular diseases (CVD). Fibrotic changes in obesity include several molecular processes, including activation of Transforming growth factor β (TGF-β). Recent data indicate the involvement of Fibroblast growth factor 21 (FGF-21) as an important metabolic regulator, and even biomarker of metabolic changes in obesity and T2DM.Aim: To determine TGF-β and FGF-2...

ea0070aep272 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Difficulties in diagnosing of artificial hypoglycemia: Insulin analogues

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina , Malysheva Natalia , Nikankina Larisa

Introduction: One of the manifestations of Munchausen syndrome is the deliberate injection of insulin to achieve hypoglycemia or artificial hypoglycemia. If human insulin is injected, we will always determine high level of insulin and low level of Cpeptideatthemomentofhypoglycemia. Incasesof insulin analogues injection the diagnos is maybe difficult when we use analyzers specific only to human insulin: the low level of IRI and C peptide will be determined.<p class="abstext...

ea0070aep314 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Antibodies to insulin receptor in the diagnosis of non-diabetic hypoglycemia

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina , Malysheva Natalia , Nikankina Larisa

Introduction: One of the autoimmunenon-diabetic hypoglycemia (NDH) causes isthe antibodies to insulinreceptor (AB-rIRI) formation and/orinsulin resistance type B (TBIR).Objectives: To determine the prevalence of increased AB-rIRI level in patients with suspected NDH of different genesis and in healthy individuals; to determine significance of AB-rIRI investigation in NDH diagnosis.Methods: In a prospective study we determined AB-rI...

ea0070ep192 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Autoimmune hypoglycemia: Hirata disease

Yukina Marina , Nuralieva Nurana , Troshina Ekaterina , Zuraeva Zamira , Nikankina Larisa

Introduction: One of the autoimmune non–diabetic hypoglycemia (NDH) causes is the formation of antibodies to insulin (AB–IRI) or Hirata disease (HD).Objectives: To determine the prevalence of AB–IRI level increasing in patients with suspected NDH of various genesis and in healthy individuals.Methods: 96 patients aged 18–80 years with suspected NDH were included in prospective study. In all patients we determ...

ea0056p46 | Adrenal cortex (to include Cushing's) | ECE2018

The measurement of the renin–angiotensin–aldosterone system in patients with adrenal tumors with arterial hypertension

Romanova Natalia , Platonova Nadezhda , Molashenko Natalia , Nikankina Larisa , Troshina Ekaterina

Introduction: This problem has a major social and medical significance. The prevalence of secondary endocrine hypertension is around 40%, of which primary aldosteronism is up to 15% and is usually developed at working age. Despite of improvement of diagnostical two-step method of finding primary aldosteronism, none of these test results can be considered reliable because of false positive and false negative results. That’s why the problem of endocrine hypertension diagnos...

ea0081ep785 | Pituitary and Neuroendocrinology | ECE2022

Clinical case of syndrome of inappropriate secretion of antidiuretic hormone (SIADH) with uncertain localization

Pigarova Ekaterina , Dzeranova Larisa , Katamadze Nino , Fargieva Khava , Malysheva Natalya , Nikankina Larisa , Przhiyalkovskaya Elena

Introduction: The syndrome of inappropriate secretion of antidiuretic hormone (SIADH) is characterized by hypotonic and euvolemic hyponatremia along with urinary hyperosmolarity, resulting from antidiuretic hormone (ADH) release in the absence of adequate stimuli.Case report: A 59-year-old woman, presented with complaints of constant thirst, general weakness, memory loss, episodes accompanied by headaches, leg cramps, increased blood pressure. From the a...