Endocrine Abstracts

A 71 year old gentleman presented with polydipsia, polyuria and nocturia for two weeks and weight loss of 10.5 Kg over the preceding two years. He had hypertension controlled with valsartan, hydrochlorthiazide, amlodipine and doxazosin. His average alcohol intake was 55 units per week. His brother had diabetes of uncertain aetiology. Examination was unremarkable apart from mild dehydration. His body mass index was 28 kg/m2 and there...

A 71 year old gentleman presented with polydipsia, polyuria and nocturia for two weeks and weight loss of 10.5 Kg over the preceding two years. He had hypertension controlled with valsartan, hydrochlorthiazide, amlodipine and doxazosin. His average alcohol intake was 55 units per week. His brother had diabetes of uncertain aetiology. Examination was unremarkable apart from mild dehydration. His body mass index was 28 kg/m2 and there...

Introduction: Subclinical hypothyroidism (SCH) is recognised as an increased risk for cardiovascular disease (CVD). Low number of circulating endothelial progenitor cells (EPC), defined as mononuclear cells, expressing endothelial (vascular endothelial growth factor receptor, VEGFR-2) and stem cell (CD-34, CD-133) markers is associated with CVD. Our aim was to identify whether reduced EPC number might contribute to increased CV risk in subclinical and overt hypothyroidism (Hy)...