Searchable abstracts of presentations at key conferences in endocrinology

ea0019s29 | The endoplasmic reticulum – an important link between inflammation, stress and metabolism | SFEBES2009

Glucose sensing in the endoplasmic reticulum: maintaining the cellular environment

Lavery G G

It is becoming increasingly evident that pathways exist within the (ER) that can impact upon cellular redox status, glucocorticoid metabolism and glucose homeostasis.Within the ER of the liver, glucose-6-phosphatase (G6Pase) and glucose 6-phosphate (G6P) transporter (G6PT) work together to increase blood glucose concentrations by performing the terminal step in both glycogenolysis and gluconeogenesis. The G6Pase ‘shares’ G6P with hexose-6-phosp...