Searchable abstracts of presentations at key conferences in endocrinology

ea0099p180 | Late-Breaking | ECE2024

Immunohistochemistry in the differential diagnosis of atypical tumor and parathyroid carcinoma

Kim Ekaterina , Lavreniuk Anastasiia , Elfimova Alina , Eremkina Anna , Selivanova Lilia , Salimkhanov Rustam , Mokrysheva Natalia

Background: Atypical parathyroid tumor (APT) generally has a better prognosis compared to parathyroid carcinoma (PC). The differential diagnosis of APT and PC is crucial for further management. Diagnosis of both is based on morphological examination but sometimes can be challenging. In such cases immunohistochemistry (IHC) should be used.Objective: To estimate the utility of IHC in the differential diagnosis of APT and PC.Materials...

ea0099p190 | Late-Breaking | ECE2024

Severe osteoporosis in a patient with APECED: atypical presentation

Lavreniuk Anastasiia , Kim Ekaterina , Salimkhanov Rustam , Eremkina Anna , Spasskaya Olga , Mokrysheva Natalia

Hypoparathyroidism (HPT) is the most common autoimmune endocrine involvement of APECED syndrome (autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy, 79-96% cases). HPT is associated with reduced bone remodeling, abnormalities in microarchitecture and bone strength, thus low-energy fractures occur despite normal or even high bone mineral density (BMD). Other APECED components (hypogonadism, malabsorption, growth hormone deficiency etc.), may also affect bone metabol...

ea0099ep1237 | Late Breaking | ECE2024

Therapeutic options in the control of refractory hypercalcemia due recurrent parathyroid carcinoma: a case series

Spasskaya Olga , Kim Ekaterina , Salimkhanov Rustam , Lavreniuk Anastasiia , Eremkina Anna , Mokrysheva Natalia

Introduction: Parathyroid carcinoma (PC) is one of the rarest malignant endocrine neoplasms (0.005% of all oncological diseases). PC relapses in 40-60% cases. The severity of the disease is determined by life-threatening hypercalcemia. Surgery is the gold treatment standard of primary tumors and distant metastases, but if it is contraindicated there are few options to control life-threatening hypercalcemia.Case 1: A 36-year-old-woman with a recurrent par...