ea0040p4 | (1) | ESEBEC2016
Ferreira Luciana Bueno
, Tavares Catarina
, Pestana Ana
, Leite Catarina
, Eloy Catarina
, Rios Elisabete
, Celestino Ricardo
, Batista Rui
, Sobrinho-Simoes Manuel
, Gimba Etel
, Soares Paula
Osteopontin (OPN) is a matricellular protein highly expressed in cancer cells, which is able to modulate tumorigenesis and metastasis in several malignancies, including follicular cell-derived thyroid cancers (TC). OPN is one of the gene products aberrantly expressed in TC, but the contribution of each OPN isoform (OPNi), named as OPNa, OPNb and OPNc, is currently unknown. This study aims to analyze the expression profile of OPNi in TC tissue samples, correlate its expression ...