ea0026p192 | Pituitary | ECE2011
Olarescu C
, Ueland T
, Lekva T
, Dahl T B
, Aukrust P
, Halvorsen B
, Bollerslev J
Background: Nicotinamide phosphoribosyltransferase (NAMPT)/PBEF/visfatin is a widely expressed cytokine with various effects on glucose and lipid metabolism, cell survival, and inflammation. Despite a favorable body composition profile, acromegalic patients present insulin resistance, increased cardiovascular risk, and higher incidence of secondary tumors.Aim: Based on its relation to glucose and lipid metabolism and inflammation we hypothesized that NAM...