Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep103 | Steroids, development and paediatric endocrinology | ECE2015

Leptin and kisspeptin evaluation in childhood obesity

Leo Francesco , Mancini Antonio , Segni Chantal Di , Raimondo Sebastiano , Barini Angelina , Curro Diego , Rossodivita Aurora Natalia

Kisspeptin is a neuropeptide secreted in anteroventral-periventricular and arcuate hypothalamic nuclei involved pubertal onset and in other functions of adult life. Kisspeptin levels are sex dependent, so they are higher in prepubertal girls and in adult women compared to age-matched male. This sex-related pattern has been reported in adult obesity, but few data are reported in childhood obesity. In order to evaluate correlations between metabolic status and kisspeptin, we stu...

ea0035p766 | Obesity | ECE2014

Vertebral bone marrow fat is increased in obese women: relationship with epicardial fat

Ermetici Federica , Briganti Silvia , Delnevo Alessandra , Cannao Paola , Secchi Francesco , Leo Gianni Di , Bandera Francesco , Dozio Elena , Romanelli Massimiliano Marco Corsi , Sardanelli Francesco , Morricone Lelio , Malavazos Alexis Elias

Introduction: Bone marrow fat is considered a risk factor for osteoporosis and fragility fracture. It is not clear if bone marrow adiposity is increased in obesity and how it relates to other compartments of adipose tissue, in particular visceral adipose tissue (VAT), subcutaneous adipose tissue (SAT), and epicardial adipose tissue (EAT).Aim: To evaluate bone marrow adiposity in obese as compared with normal weight women.Design: Tw...

ea0035p923 | Pituitary Clinical (<emphasis role="italic">Generously supported by IPSEN</emphasis>) | ECE2014

Relationship between growth hormone deficiency and oxidative stress in patients with heart failure: Preliminary data.

Mancini Antonio , Raimondo Sebastiano , Segni Chantal Di , Gadotti Giovanni , Leo Francesco , Ierardi Carolina , Silvestri Sonia , Orlando Patrick , Tiano Luca , Pontecorvi Alfredo

It is well known that heart failure is associated with oxidative stress (OS). Reactive oxygen species in fact influence sarcolemmal and mitochondrial ione channels, which are responsible for cardiomyocyte excitability and are important in myocardial remodeling after a myocardial infarction. The decrease of anabolic axes can have a role in the progression of the illness.In order to evaluate the relationship between growth hormone deficiency (GHD) and inde...