Searchable abstracts of presentations at key conferences in endocrinology

ea0049ep1167 | Male Reproduction | ECE2017

Early arterial stiffness and chronic inflammation in male equivalents of polycystic ovary syndrome

Sozen Mehmet , Baldane Suleyman , Abusoglu Sedat , Kebapcilar Levent , Kebapcilar Aysegul , Akyurek Fatma , Unlu Ali , Ipekci Suleyman Hilmi

Introduction: There is some evidence that a rise in the androgen hormone levels increases the risk for the development of a cardiovascular disease, obtained from the studies conducted on women with polycystic ovary and on men with androgenic alopecia. Inflammatory substances tend to increase in polycystic ovary syndrome and in androgenic alopecia. On this basis, we conducted a study that aimed to evaluate the early cardiovascular and metabolic effects in male patients with and...

ea0014p389 | (1) | ECE2007

Abnormal calcium metabolism as shown by the Ellsworth-Howard test and its relation to pseudohypoparathyroidism II

Kebapcilar Levent , Yesil Sena , Demir Tevfik

Peudohypoparathyroidism is a heterogenous group of disorders characterized by hypocalcemia, hyperphosphatemia, increased serum concentration of parathormone, and insensivity to biological activity of parathormone.A 45-year-old female was admitted to the regional hospital for check up and routine laboratory studies revealed slightly decreased level of calcium. Her neurologic examination was negative for Chvostek’s and Trousseau’ signs. Laborator...

ea0056p317 | Clinical case reports - Thyroid/Others | ECE2018

Diabetic ketoacidosis occurring in the patient whom newly started insulin glargine U300: a case report

Onur Kirac Cem , Ipekci Suleyman , Kebapcilar Levent

Basal insulin secretion is essential for the maintenance of fasting glucose levels, especially through inhibition of excessive hepatic glucose output. Insulin glargine U300 is a novel long acting basal insulin formulation that provides more stable effect than glargine U100. Because of the pharmacokinetic properties of glargine U300, the expected plasma insulin concentration is not achieved during the first 4 days of treatment. We report a case of diabetic ketoacidosis in the f...

ea0049ep256 | Calcium & Vitamin D metabolism | ECE2017

Spontaneous remission of parathyroid adenoma due to parathyroid apoplexy: a case report

Kirac Cem Onur , Baldane Suleyman , Ipekci Suleyman , Kebapcilar Levent

Introduction: Primary hyperparathyroidism (PHPT) is a disease that is characterized by elevated calcium and parathyroid hormone levels. The most common cause of PHPT is the paratiroid adenoma and the first line treatment option is surgical removal of the adenoma. Rarely, the haemorrhage in the lesion may cause the spontaneous remission of the disease.Case report: A 54-year-old woman patient with fatigue was referred to our department due to calcium level...

ea0049ep419 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Is secreted frizzled-releated protein 4 (SFRP-4) a possible biomarker for β cell dysfunction?

Baldane Suleyman , Ipekci Suleyman , Abusoglu Sedat , Unlu Ali , Kebapcilar Levent

Introduction: SFRP-4 is a recently described inflammatory cytokine influencing insulin secretion from human β cells as an extracellular modulator of Wingless (Wnt) pathway. The aim of this study is to compare serum SFRP-4 levels in patients with normal glucose tolerance (NGT), impaired glucose tolerance (IGT) and type 2 diabetes (T2DM), and to investigate its relation with other parameters.Methods: The study included 152 patients who applied to the ...

ea0049ep1214 | Clinical case reports - Thyroid/Others | ECE2017

Papillary thyroid microcarcinoma in struma ovarii tissue: a case report

Kirac Cem Onur , Baldane Suleyman , Ipekci Suleyman , Kebapcilar Levent

Introduction: Struma ovarii is an uncommon ovarian neoplasm that more than half of itself is made up of thyroid tissue. In clinical trials about the disease, malign transformation has been detected at the rate of 0.5–5%. Because of the disease’s rareness, there is no absolute agreement about diagnosis and treatment of the disease.Case report: A 33-year-old woman admitted to gynecology department with abdominal pain. Her pelvic MR revealed 147&#...

ea0056p985 | Clinical case reports - Thyroid/Others | ECE2018

A silent thyroiditis in the remission period of Graves’ disease

Kirac Cem Onur , Ipekci Suleyman , Gedik Gonca Kara , Kebapcilar Levent

Silent thyroiditis is characterized by the destructive thyroid inflammation and is considered to be a chronic autoimmune thyroid disease, although the etiology could not have been fully explained. On the other hand, Graves’ disease is autoimmune phenomena as well as silent thyroiditis and silent thyroiditis has been classified as part of the spectrum of Graves’ disease. Although, the thyroid stimulating antibody (TSAb) are found positive in most of Graves’ disea...

ea0049ep421 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Effect of glucose ingestion on serum fractalkine levels in healthy subjects and diabetic patients

Baldane Suleyman , Kendir Ismail Can , Ipekci Suleyman , Tekin Gulsum , Unlu Ali , Kebapcilar Levent

Introduction: Current studies suggest that fractalkine (FKN) could be a pathogenic factor associated with adipocyte dysfunction and type 2 diabetes (T2DM) and have shown that FKN serum levels are increased in T2DM patients. The aim of this study was determined as evaluating the change of FKN levels that will occur with oral glucose tolerance test (OGTT).Methods: The study included 67 patients to whom OGTT was applied. The patients with the history of dia...

ea0035p69 | Bone and Osteoporosis | ECE2014

Subclinical celiac disease presented with postpartum low-back pain: case report

Baldane Suleyman , Ipekci Suleyman , Sahin Fatih , Baldane Emine , Karabagli Pinar , Kebapcilar Levent , Kanat Mustafa

Introduction: There are serological findings and mucosal injury similar to the classical form but no gastrointestinal symptoms in subclinical Celiac disease (CD). In this article, we present a case of subclinical CD presented with postpartum low-back pain, in whom we discovered severe lumbar vertebral osteoporosis.Case report: A 35-year-old woman admitted to our outpatient clinic with severe low-back pain. The patient had given birth 5 months ag...

ea0014p289 | (1) | ECE2007

The effects of subclinical hypothyroidism and replacement therapy on paraoxonase-1 (PON-1) and common carotis intima media thickness

Kebapcilar Levent , Comlekci Abdurrahman , Tuncel Pinar , Solak Ahmet , Secil Mustafa , Gencel Omur , Yesil Sena

The mechanism of atherosclerosis in patients with subclinical hypothyroidism (sHT), which has been partly attributed to lipid abnormalities, is still controversial. There is substantial evidence that ox-LDL plays an important role during the atherosclerosis process and paraoxonase-1 (PON-1) significantly inhibits generation of lipid peroxidation and thus plays a role in against atherosclerosis. The aim of the study was evaluate qualitative changes in lipoprotein metabolism, hs...