Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep240 | Calcium and Vitamin D metabolism | ECE2015

Recalcitrant hypocalcaemia in a patient with post-thyroidectomy hypoparathyroidism and roux-en-y gastric bypass

Miguel Gonzalo Allo , Fernandez Elena Garcia , Librizzi Soledad , Diaz-Guerra Guillermo Martinez , Carranza Federico Hawkins

Introduction: Roux-en-Y gastric bypass (RYGB) places patients at an increased risk of hypocalcemia due to the reduction in calcium absorption (because the procedure bypasses the duodenum and jejunum) and vitamin D deficiency. Subsequent thyroid surgery increases the risk of severe hypocalcemia due to potential post-operative hypoparathyroidism. Only a few cases have been published before of this kind of treatment-challenging hypocalcaemia.Case report: We...

ea0067o46 | Oral Presentations | EYES2019

Effect of treatment with Cinacalcet on TBS and BMD in patients with chronic renal failure with secondary hyperparathyroidism in hemodialysis

Reyes Laura Mola , Maria Soledad Librizzi , Martinez Eduardo Hernandez , Herrero Eva Merida , Cuellar Hernando Trujillo , Arriscado Cristina Martin , Carranza Federico Hawkins

Background: Fractures are frequent in patients with chronic renal failure (CRF) with secondary hyperparathyroidism (SHPT) undergoing hemodialysis. Cinacalcet (CT) is a drug used in the reduction of hypercalcemia in these patients that acts through the lintel calcium sensor in the parathyroid gland. Recently, it has been pointed out that CT can reduce fractures in these patients by unknown mechanisms (EVOLVE Trials 2015).Objectives: To evaluate the effect...

ea0041ep40 | Adrenal cortex (to include Cushing's) | ECE2016

Analysis of 176 cases of adrenal incidentaloma investigated in a single clinical center, what are we doing?

Jimenez Maria Maiz , Gutierrez Maria Calatayud , Bracamonte Milagros Sierra , Librizzi Soledad , Nino Virginia Rodriguez , Munoz Myriam Lorena Partida , Carranza Federico Hawkins

Introduction: Patients referred for adrenal incidentalomas (AI) are increasing. Current guidelines are controversial on diagnosis and length of follow-up.Objectives: Analyze clinical, radiologic and hormonal characteristics of patients with AI. Evaluate the number and usefulness of tests needed for diagnosis, clinical outcome and follow up.Material and methods: Observational, retrospective study in patients with AI in our endocrino...

ea0037ep268 | Calcium and Vitamin D metabolism | ECE2015

Patients with new onset diabetes after liver transplantation have higher sclerostin levels that tend to decrease after an oral glucose tolerance test

Diaz-Guerra Guillermo Martinez , Miguel Gonzalo Allo , Ramos Mercedes Aramendi , Librizzi Soledad , Iglesias Sonsoles Guadalix , Fernandez Elena Garcia , Carranza Federico Hawkins

Introduction: Decreased bone formation has been proposed as a mechanism involved in the higher risk of fractures in diabetic patients. Some clinical studies have found that sclerostin (SCL, a negative regulator of bone formation) is increased in diabetic patients. However, there is no information about the relationship between SCL and new onset diabetes after transplantation (NODAT). The aim of our study is to evaluate serum SCL levels in a cohort of patients with liver transp...

ea0056p760 | Neuroendocrinology | ECE2018

Postoperative basal serum cortisol as a predictor of long-term hypothalamic-pituitary-adrenal axis integrity after endonasal transsphenoidal surgery for sellar and suprasellar masses

Males Maldonado David , Martin Alba , Librizzi Soledad , Martin-Arriscado Cristina , Paredes Igor , Fernandez Alen Jose , Lagares Alfonso , Aramendi Mercedes , Calatayud Maria

Introduction: Endonasal endoscopic transsphenoidal surgery (EETS) for a sellar or suprasellar mass poses potential complications, including transient or permanent hypopituitarism. Adrenocortical insufficiency is especially worrisome given its potentially life-threatening course, if untreated. Usual clinical practice includes administration of perioperative “stress doses” of steroids followed by long term steroid replacement until the hypothalamic-pituitary-adrenal ax...

ea0056p832 | Pituitary - Clinical | ECE2018

Trabecular bone score as skeletal fragility predictor in patients with acromegaly

Perez-Olivares Martin Laura , Calatayud Gutierrez Maria , Soledad Librizzi Maria , Gonzalez Mendez Violeta , Guadalix Iglesias Sonsoles , Hawkins Carranza Federico , Martinez Diaz-Guerra Guillermo

Introduction: Several studies have demonstrated a high incidence of vertebral fractures (VF) in acromegaly, not always correlated with bone mineral density (BMD) value adquired by dual X-ray absorptiometry (DEXA). At trabecular level, GH may alter bone microarchitecture (BM) that predisposes to bone fragility. Trabecular Bone Score (TBS), a textural parameter applied to DEXA to evaluate BM, could be useful to predict VF risk in these patients.Materials a...

ea0063p1106 | Pituitary and Neuroendocrinology 3 | ECE2019

Analysis of gender-related differences in clinically non-functioning pituitary adenomas

Aguirre Moreno Nerea , Sampedro-Nunez Miguel , Levi Ana Ramos , Centeno Rogelio Garcia , Carrera Concepcion Blanco , Escola Cristina Alvarez , Novoa Paz de Miguel , Gutierrez Maria Calatayud , Librizzi Soledad , Azpiroz Monica Marazuela

Introduction: Clinically non-functioning pituitary adenomas (NFPA) are heterogeneous group. Some previous research has found that this type of pituitary adenomas may be smaller and have better prognostic in men. The aim of this study is to analyze if there are gender-related differences in NFPA.Material and methods: Retrospective study of patients with NFPA followed up in regional hospitals (Community of Madrid, Spain). All NFPA had molecular analysis. T...