Endocrine Abstracts

Background: Iatrogenic adrenal insufficiency (AI) refers to primary, secondary, or tertiary hypoadrenalism associated with drug administration, surgery, or irradiation. The most common cause of secondary adrenal insufficiency is exogenous glucocorticoids. Hepatic metabolism of inhaled corticosteroids (ICS) takes place via cytochrome P450 3A4. Nevertheless, it can be decreased by enzyme inhibitors such as itraconazole or ritonavir, thus leading to an increase in the bioavailabi...

Milk – alkali syndrome is a rare and distinctive disorder caused by ingestion of large amounts of calcium and absorbable alkali resulting in hypercalcemia. It is characterized by a triad of hypercalcemia, metabolic alkalosis and renal failure. Here we present a 59 years old female patient, who presented to Emergency department for a fall and Syncopal episode. She had a few days history of increasing thirst, polyuria and diffuse abdominal discomfort. This prior to her sync...