Searchable abstracts of presentations at key conferences in endocrinology

ea0037ep408 | Diabetes (complications & therapy) | ECE2015

Microalbuminuria in children and adolescents with type 1 diabetes mellitus: predictive factors

Nunes Joana , Monteiro Ricardo , Amaral Daniela , Pina Rosa , Lopes Lurdes , Limbert Catarina

Objective: Microalbuminuria is usually the first microvascular complication of type 1 diabetes mellitus (T1DM). We aimed to identify its frequency, time of occurrence and related risk factors.Methods: Clinical reports of 201 children followed in our institution were retrospectively analysed (diabetes duration 3.8±3.6 years, age at diagnosis 8.1±3.7 years, HbA1c value 9.0±1.7%). Statistical analysis was performed with SPSS version.21 for Wi...

ea0035p807 | Paediatric endocrinology | ECE2014

Usefulness of ACTH stimulation in the differential diagnosis of precocious pubarche

Santos Maria Joana , Amaral Daniela , Limbert Catarina , Pina Rosa , Lopes Lurdes

Introduction: Nonclassical congenital adrenal hyperplasia (NCCAH) is caused by reduced 21-hydroxylase activity, leading to excessive adrenal androgens and premature pubarche (PP); idiopathic PP (IPP) is its main differential diagnosis. The gold standard for the differential diagnosis is ACTH stimulation test (ST); this test also estimates the adrenal cortisol reserve in NCCAH patients.Objectives: To compare the clinical characteristics and baseline hormo...

ea0032p806 | Paediatric endocrinology | ECE2013

Obesity and thyroid function in children: cross-sectional study

Limbert Catarina , Santos Maria Ines , Rosario Frederico , Amaral Daniela , Pina Rosa , Oliveira Laura , Lopes Lurdes

Obesity and thyroid function in children – cross-sectional study.Background: Obesity in children has been increasing dramatically, with a significant increase in cardiovascular and metabolic diseases risk. The role of thyroid dysfunction has been extensively analyzed in obese adults, but to a limited extent in children.Aims: To estimate the prevalence of hyperthyrotropinemia in obese children and to analyze the influence of BM...

ea0049ep887 | Growth hormone IGF axis - basic | ECE2017

Somatropin treatment Supported by NHS: characterization of submitted patients – 2006 to 2016

Bastos Margarida , Mirante Alice , Afonso Caldas , Vasconcelos Carlos , Bacelar Conceicao , Pereira Conceicao , Lopes Lurdes , Fonseca Marcelo , Serra-Caetano Joana , Patricio Miguel , Esteves Cesar Marques , Ferreira Florbela , Braganca Graciete , Raimundo Luisa , Matos Lurdes , Sampaio Lurdes , Fontoura Manuel , Borges Teresa

Introduction: In our country somatropin treatment is supported by the National Health Service. A National Committee (CNNHC) rules and analysis the submission papers of patients with: isolated/multiple somatotropin deficiency (STD), short stature in: renal chronic disease (DRC), small for gestational age (SGA), Turner syndrome (TS) and Prader Willi syndrome (PWS). In adults only isolated somatropin deficiency diagnosed in childhood.Aims: To analyze the ch...

ea0056p728 | Developmental endocrinology | ECE2018

CNNHC: Preliminary results of treatment with recombinant somatropin

Bastos Margarida , Mirante Alice , Marques Bernardo , Caetano Joana Serra , Afonso Caldas , Vasconcelos Carlos , Bacelar Conceicao , Pereira Conceicao , Lopes Lurdes , Fonseca Marcelo , Patricio Miguel , Esteves Cesar , Ferreira Florbela , Braganca Graciete , Raimundo Luisa , Matos Lurdes , Foutoura Manuel , Borges Teresa

Introduction: Treatment with recombinant Somatropin (rSMT) is safe and has greatly improved the approach of children and adolescents with somatropin deficiency (SMTD) and other growth disorders. In our country, rSMT therapy is approved for isolated/multiple somatropin deficiency, small for gestational age (SGA), chronic kidney disease (CKD), Turner syndrome (TS) and Prader Willi syndrome (PWS). A National Commitee (CNNHC) is responsible for the analysis of each case and treatm...