Searchable abstracts of presentations at key conferences in endocrinology

ea0016p781 | Thyroid | ECE2008

Iodine status in pregnant women: do they have sufficient information about the importance of iodine nutrition during the pregnancy?

Marco Amparo , Vicente Almudena , Castro Enrique , Canovas Barbara , Sastre Julia , Cruces Eva , Maqueda Esther , Iglesias Maria Lopez , Lopez Jose Lopez

The recommended nutrient intake (RNI) for iodine during pregnancy has been re-evaluated in 2005 by an international expert committee under the auspices of the World Health Organization (WHO). The consensus reached was that the RNI for iodine during pregnancy should range between 200 and 300 μ/d with an average of 250 μ/d.To asses the adequacy of the iodine intake during pregnancy in a population, urinary iodine concentration (UIC) should be mea...

ea0063p249 | Pituitary and Neuroendocrinology 1 | ECE2019

Spontaneous pregnancy obtained in persistent Cushing Disease treated with Cabergoline: Report of two cases

Vicente Almudena , Castro Enrique , Cruz Andrea , Castro Ana , Julia Sastre , Jose Lopez

Introduction: Pregnancy is rare in patients with Cushing Disease (CD) owing to ovulatory dysfunction. When surgery is not curative, medical treatment is usually considered. Ketoconazole and mitotane, commonly used medical therapies, have questionable teratogenicity and are not often options in pregnancy. Cabergoline was found to be effective in reducing hypercortisolism in Cushing’s disease. Observational studies suggested that low dose cabergoline treatment at the time o...

ea0049ep973 | Pituitary - Clinical | ECE2017

Clinical, histological, molecular features and outcomes of craniopharyngiomas: Single centre experience in Toledo, Spain

Vicente Almudena , Moreno Beatriz , Olivar Monica , Martinez Ana , Mollejo Manuela , Sastre Julia , Lopez Jose

Background: Craniopharyngiomas (CPs) are epithelial tumors that typically arise in the suprasellar region. They are associated with high levels of morbidity related to tumour location and/or treatment-related injuries. Recent discoveries have also led to a better understanding of CP development and potential treatments.Objetive: To analyse the clinical, pathological, molecular features and outcomes of patients with CP.Design: Retro...

ea0041ep544 | Diabetes therapy | ECE2016

Potential glycemic overtreatment in diabetics patients older than 70 years and comorbid conditions: real-life experience

Vicente Almudena , Olivar Monica , Cortes Claudia , Martinez Ana , Sastre Julia , Pena Virginia , Canovas Barbara , Lopez Jose

Background: Optimal glucose management in older people is currently unclear. Recent guidelines recommend avoiding tight glycemic targets in elderly patients with comorbidities because intensive control is unlikely to achieve benefit and they are at higher risk of hypoglycaemia.Objective: To estimate the prevalence of potential overtreatment in older adults with diabetes mellitus and comorbidities.Design: Cross-sectional study.<...

ea0041ep576 | Diabetes therapy | ECE2016

Trends and differences between sexes in control of diabetes and cardiovascular risk factors from 2004 to 2014

Vicente Almudena , Cortes Claudia , Olivar Monica , Martinez Ana , Sastre Julia , Marco Amparo , Luque Ines , Lopez Jose

Background: Poorer control of risk factors for cardiovascular disease (cvd) has been reported in diabetic women compared with men.Objective: To investigate whether control of diabetes and risk factors for cvd differ between sexes in a cohort of diabetic patients monitored at an outpatient endocrinology clinic from 2004 till 2014.Design: Observational, retrospective cohort study.Patients and methods: A cohort ...

ea0037ep1039 | Thyroid (non-cancer) | ECE2015

Descriptive analysis of the histopathological findings of a series of 1567 thyroidectomies

Ma Calderon Dulce , Delgado Manuel , Castro Enrique , Alfaro Jose Joaquin , Lopez Gema , Lopez Jose , Aranda Jaime

Introduction: We wanted to analyse the pathology results of thyroidectomies performed in the hospitals of Castilla La Mancha (Spain) between the years 2010 and 2013, inclusive.Material and methods: A retrospective, multicentre, descriptive study of the histopathological results of the 1567 thyroidectomies performed in the hospitals of the eight health districts in our region between the years 2010 and 2013.Results: The histopatholo...

ea0032p482 | Diabetes | ECE2013

Are there gender differences in liraglutide response in adults with type 2 diabetes?

Sastre Julia , Vicente Almudena , Maqueda Esther , Luque Ines , Castro Enrique , Marco Amparo , Pena Virginia , Lopez Jose

Background: Recent reports suggest that female sex could be an indicator of better response to liraglutide in patients included in clinical trials.Aim: To compare efficacy of liraglutide in women and men with type 2 diabetes mellitus (T2DM), in real clinical practice.Patients and methods: Our study included 116 patients with T2DM and obesity (BMI >30) attending outpatient clinic, which initiated with liraglutide (0.6 mg/daily f...

ea0022p336 | Diabetes | ECE2010

Therapeutic objectives in the care of patients with diabetes mellitus type 2 in clinical practice at an endocrine department

Jimenez Carmen Tenorio , Ibarra Pablo Jose Lopez , Munoz Manuel Romero , del Valle Maria Jimenez

According to the American Diabetes Association (ADA), achieving specific treatment goals in type 2 diabetes can substantially reduce microvascular complications, including retinopathy, nephropathy and neuropathy. Intensive management has also been shown to have a beneficial effect on cardiovascular disease. The objective of the study is to evaluate the degree of achievement of appropriate target levels for A1C, as an index of chronic glycaemia, LDL-c and blood pressure, in a l...

ea0016p272 | Endocrine tumours | ECE2008

Special multiple endocrine neoplasia (MEN)

Santiago Piedad , Ramirez Cesar , Ruiz Isabel , Martinez Pilar , Lopez Jose Antonio , Sanchez Carolina , Moreno Alberto

The ‘Multiple Endocrine Neoplasia’ predominantly affect the pituitary gland, parathyroids, thyroids, adrenal glands and pancreas. We present the case of a patient with three different functioning endocrine gland tumours, but who cannot be included in any of these groups.Case report: Sixty-five-years-old female with recurrent episodes of nephritic colic and hypertension for 2 years; non-specific gastrointestinal complaints, hirsutism, hyp...

ea0016p807 | Thyroid | ECE2008

Clinical variables associated with recurrence of hyperthyroidism in Graves’ disease

Cristina Familiar , Inmaculada Moraga , Eva Cruces , Almudena Vicente , Julia Sastre , Jose Lopez

Introduction: In Graves’ hyperthyroidism with long-term antithyroid drugs (ATD) treatment, remission is often umpredictable. However variables at diagnosis or at the end of the ATD regimen are associated with a highest likelihood of recurrence and could be used to decide an ablative treatment.Objective: To identify variables before and at the end of a long-term treatment with ATD (>6 months) associated with higher rates of relapse during a follo...