ea0081p736 | Thyroid | ECE2022
Colonnello Elena
, Curreli Mariaignazia
, Tozzi Rossella
, Criniti Anna
, Lorusso Emiliano
, Gnessi Lucio
, Gandini Orietta
, Lubrano Carla
Background: The relationships between thyroid hormones (TH) and platelets (PLT) have not been fully established. Physiological concentrations of L-thyroxine (T4) activate human PLT resulting in ATP release and aggregation. On the other hand, subclinical hypothyroidism has been frequently associated with hypercoagulability, in particular mean platelet volume (MPV), a marker of platelet activation, has been found higher in patients with subclinical hypothyroidism. A possible pro...