Endocrine Abstracts

Background: Adrenal involvement in multiple endocrine neoplasia type 1 (MEN1) has been reported, its prevalence varying from 9 to 73%. The aim of this study was to characterize the adrenal phenotype and the prevalence and clinical significance of cortisol hypersecretion in a cohort of MEN1 patients.Methods: We retrospectively analyzed data of 36 adult patients with germline menin mutation (20 females; mean age 50±17.4 years) in regular follow-up at ou...

Background: Psychopathological distress is a significant burden in acromegaly, mostly in terms of depression and anxiety. Patients are also reported to experience an impairment in cognitive performance, yet literature is highly heterogeneous.M&M: We conducted a cross-sectional study recruiting 44 acromegalic patients (59% females, 29.5% with active disease, 70.5% controlled/in remission) referring to our tertiary center between 2011 and 2023 and 40 h...

Background: In the last few decades, the association between pituitary disorders and cardiovascular disease has been demonstrated. Furthermore, the importance of gender as a non-modifiable risk of factor is increasingly emerging.Methods: We retrospectively analyzed data of 112 patients diagnosed with nonfunctioning pituitary tumor (NFPT) attending the outpatient clinic at our tertiary center. In this study we report only preliminary data of the retrospec...