ea0063gp231 | Adrenal and Neuroendocrine - Clinical (1) | ECE2019
, Gourdin Louis
, Briet Claire
, Rodien Patrice
, Munier Mathilde
Bisphenol A (BPA) is a widely used chemical and belongs to the list of metabolism-disrupting chemicals. BPA is banned in several countries and replaced by others BPA-analogs. We investigate the effects of BPA and 6 BPA-analogs (BPS, BPAF, BPF, BPB and BADGE) on the response of the human melanocortin 4 receptor (MC4R), a receptor involved in food intake and weight control, to its natural ligands. We used HEK293 cells line transiently transfected with human MC4R to determine the...